The secretory granule‐mediated cell death pathway is the key mechanism for elimination of
virus‐infected and transformed target cells by cytotoxic lymphocytes. The formation of the …

Cerebral malaria is a severe neuropathological complication of Plasmodium falciparum
infection. It results in high mortality and post-recovery neuro-cognitive disorders in children …

Background Cerebral malaria (CM) is a neurological syndrome that includes coma and
seizures following malaria parasite infection. The pathophysiology is not fully understood …

Despite decades of research, cerebral malaria remains one of the most serious
complications of Plasmodium infection and is a significant burden in Sub-Saharan Africa …

Brain hemodynamics in cerebral malaria (CM) is poorly understood, with apparently
conflicting data showing microcirculatory hypoperfusion and normal or even increased …

Hyperbaric oxygen (HBO) therapy is a well-established method for improving tissue
oxygenation and is typically used for the treatment of various inflammatory conditions …

Dendritic cells (DCs) are activated by pathogens to initiate and shape immune responses.
We found that the activation of DCs by Plasmodium falciparum, the main causative agent of …

Homeostasis of mammalian cell function strictly depends on balancing oxygen exposure to
maintain energy metabolism without producing excessive reactive oxygen species. In vivo …

Objective: To investigate the therapeutic roles of hyperbaric oxygen exposure on high-
altitude pulmonary edema and to determine whether aquaporin-1 and aquaporin-5 were …

Cerebral malaria (CM) is associated with high mortality and risk of sequelae, and
development of adjunct therapies is hampered by limited knowledge of its pathogenesis. To …