Fingolimod rebound: a review of the clinical experience and management considerations

B Barry, AA Erwin, J Stevens, C Tornatore - Neurology and therapy, 2019 - Springer
Because the treatment of multiple sclerosis (MS) may span decades, the need often arises to
make changes to the treatment plan in order to accommodate changing circumstances …

The burden of chronic kidney disease in systemic lupus erythematosus: a nationwide epidemiologic study

A Mageau, JF Timsit, A Perrozziello, S Ruckly… - Autoimmunity …, 2019 - Elsevier
Objective To analyze the impact of chronic kidney disease (CKD) on major clinical outcome
in SLE by using a nationwide database. Patients and methods Characteristics of all admitted …

Molecular characterization of breast cancer CTCs associated with brain metastasis

D Boral, M Vishnoi, HN Liu, W Yin, ML Sprouse… - Nature …, 2017 - nature.com
The enumeration of EpCAM-positive circulating tumor cells (CTCs) has allowed estimation
of overall metastatic burden in breast cancer patients. However, a thorough understanding …

Dysregulated microRNA involvement in multiple sclerosis by induction of T helper 17 cell differentiation

C Chen, Y Zhou, J Wang, Y Yan, L Peng… - Frontiers in …, 2018 - frontiersin.org
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous
system. Growing evidence has proven that T helper 17 (Th17) cells are one of the regulators …

Multiplex analysis of cerebrospinal fluid and serum exosomes MicroRNAs of untreated relapsing remitting multiple sclerosis (RRMS) and proposing noninvasive …

M Mohammadinasr, S Montazersaheb, O Molavi… - NeuroMolecular …, 2023 - Springer
Exosomal microRNAs (miRNAs) are emerging diagnostic biomarkers for neurodegenerative
diseases. In this study, we aimed to detect relapsing–remitting multiple sclerosis (RRMS) …

Glyphosate-based herbicides at low doses affect canonical pathways in estrogen positive and negative breast cancer cell lines

E Stur, AF Aristizabal-Pachon, KC Peronni… - PLoS …, 2019 - journals.plos.org
Glyphosate is a broad-spectrum herbicide that is used worldwide. It represents a potential
harm to surface water, and when commercially mixed with surfactants, its uptake is greatly …

[HTML][HTML] Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis

Q Wu, EA Mills, Q Wang, CA Dowling, C Fisher… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Siponimod (BAF312) is a selective sphingosine-1-phosphate receptor 1
and 5 (S1PR1, S1PR5) modulator recently approved for active secondary progressive …

Immune-related miRNA expression patterns in peripheral blood mononuclear cells differ in multiple sclerosis relapse and remission

N Baulina, O Kulakova, I Kiselev, G Osmak… - Journal of …, 2018 - Elsevier
MiRNAs were shown to participate in development of autoimmune inflammatory process in
multiple sclerosis (MS). To investigate miRNAs involvement in relapse-remission MS course …

Peripheral CD39-expressing T regulatory cells are increased and associated with relapsing-remitting multiple sclerosis in relapsing patients

N Álvarez-Sánchez, I Cruz-Chamorro… - Scientific reports, 2019 - nature.com
CD39, an ectonucleotidase that hydrolyses pro-inflammatory ATP, is a marker of highly
active and suppressive T regulatory cells (Tregs). Although CD39 has a role in Treg …

Enhanced and complementary benefits of a nalfurafine and fingolimod combination to treat immune‐driven demyelination

K Robichon, R Bibi, M Kiernan, L Denny… - Clinical & …, 2023 - Wiley Online Library
Objectives Multiple sclerosis (MS) is a neurodegenerative disease characterised by
inflammation and damage to myelin sheaths. While all current disease‐modifying treatments …