Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients

G Degiacomi, JC Sammartino, LR Chiarelli… - International journal of …, 2019 - mdpi.com
Nontuberculous mycobacteria (NTM) have recently emerged as important pathogens among
cystic fibrosis (CF) patients worldwide. Mycobacterium abscessus is becoming the most …

The cell envelope of Mycobacterium abscessus and its role in pathogenesis

S Parmar, EI Tocheva - PLoS Pathogens, 2023 - journals.plos.org
Mycobacterium abscessus is a nontuberculosis mycobacterium (NTM) that has shown an
exponential rise in its ability to cause disease. Due to its ubiquitous presence in the …

Virulence Mechanisms of Mycobacterium abscessus: Current Knowledge and Implications for Vaccine Design

KC Ferrell, MD Johansen, JA Triccas… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium abscessus is a member of the non-tuberculous mycobacteria (NTM) group,
responsible for chronic infections in individuals with cystic fibrosis (CF) or those otherwise …

Extreme Drug Tolerance of Mycobacterium abscessus “Persisters”

YK Yam, N Alvarez, ML Go, T Dick - Frontiers in microbiology, 2020 - frontiersin.org
Persistence of infection despite extensive chemotherapy with antibiotics displaying low MICs
is a hallmark of lung disease caused by Mycobacterium abscessus (Mab). Thus, the …

[HTML][HTML] Antibacterial peptide RP557 increases the antibiotic sensitivity of Mycobacterium abscessus by inhibiting biofilm formation

B Li, Y Zhang, Q Guo, S He, J Fan, L Xu… - Science of The Total …, 2022 - Elsevier
Biofilm formation is an important factor for Mycobacterium abscessus to resist harsh
environment and produce drug resistance. The anti-biofilm activity of a newly designed …

Characterization of Mycobacterium abscessus colony-biofilms based on bi-dimensional images

JJ Aguilera-Correa, YM Boudehen… - Antimicrobial agents and …, 2023 - Am Soc Microbiol
Mycobacterium abscessus biofilm aggregates have been shown in the lungs of cystic
fibrosis patients and are often tolerant to drugs. Herein, we analyzed bi-dimensional images …

Understanding tolerance to cell wall–active antibiotics

T Dörr - Annals of the New York Academy of Sciences, 2021 - Wiley Online Library
Antibiotic tolerance—the ability of bacteria to survive for an extended time in the presence of
bactericidal antibiotics—is an understudied contributor to antibiotic treatment failure. Herein …

Alternative and Experimental Therapies of Mycobacterium abscessus Infections

M Meir, D Barkan - International journal of molecular sciences, 2020 - mdpi.com
Mycobacterium abscessus is a non-tuberculous mycobacterium notoriously known for
causing severe, chronic infections. Treatment of these infections is challenging due to either …

Altered serine metabolism promotes drug tolerance in Mycobacterium abscessus via a WhiB7-mediated adaptive stress response

C Bernard, Y Liu, G Larrouy-Maumus… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Mycobacterium abscessus is an emerging opportunistic pathogen responsible for chronic
lung diseases, especially in patients with cystic fibrosis. Treatment failure of M. abscessus …

A Screening of the MMV Pandemic Response Box Reveals Epetraborole as A New Potent Inhibitor against Mycobacterium abscessus

T Kim, BTB Hanh, B Heo, N Quang, Y Park… - International journal of …, 2021 - mdpi.com
Mycobacterium abscessus is the one of the most feared bacterial respiratory pathogens in
the world. Unfortunately, there are many problems with the current M. abscessus therapies …