Microfluidics‐based 3D cell culture models: Utility in novel drug discovery and delivery research

N Gupta, JR Liu, B Patel, DE Solomon… - Bioengineering & …, 2016 - Wiley Online Library
The implementation of microfluidic devices within life sciences has furthered the possibilities
of both academic and industrial applications such as rapid genome sequencing, predictive …

Biomimetic tissues on a chip for drug discovery

AM Ghaemmaghami, MJ Hancock, H Harrington… - Drug discovery today, 2012 - Elsevier
Developing biologically relevant models of human tissues and organs is an important
enabling step for disease modeling and drug discovery. Recent advances in tissue …

Animal tissue culture principles and applications

A Verma, M Verma, A Singh - Animal biotechnology, 2020 - Elsevier
Animal cell culture technology in today's scenario has become indispensable in the field of
life sciences, which provides a basis to study regulation, proliferation, and differentiation and …

Gold nanoparticle and conducting polymer-polyaniline-based nanocomposites for glucose biosensor design

V Mazeiko, A Kausaite-Minkstimiene… - Sensors and Actuators B …, 2013 - Elsevier
Two new nanocomposite structures (i) glucose oxidase (GOx) entrapped within polyaniline
(PANI) layer (GOx/PANI) and (ii) GOx, gold nanoparticles (Au-NPs) entrapped within PANI …

Droplet-based microfluidics: enabling impact on drug discovery

OJ Dressler, RM Maceiczyk… - Journal of …, 2014 - journals.sagepub.com
Over the past two decades, the application of microengineered systems in the chemical and
biological sciences has transformed the way in which high-throughput experimentation is …

Evaluation of photodynamic therapy efficiency using an in vitro three-dimensional microfluidic breast cancer tissue model

Y Yang, X Yang, J Zou, C Jia, Y Hu, H Du, H Wang - Lab on a Chip, 2015 - pubs.rsc.org
In recognition of the limitations of monolayer cell cultures and resource-intensive animal
studies, a microfluidic culture system was developed for creation of physiologically relevant …

Mimicking human pathophysiology in organ‐on‐chip devices

O Yesil‐Celiktas, S Hassan, AK Miri… - Advanced …, 2018 - Wiley Online Library
Convergence of life sciences, engineering, and basic sciences has opened new horizons for
biologically inspired innovations, and a considerable number of organ‐on‐a‐chip platforms …

Lab-on-a-chip systems for photodynamic therapy investigations

M Chudy, K Tokarska, E Jastrzębska, M Bułka… - Biosensors and …, 2018 - Elsevier
In recent years photodynamic therapy (PDT) has received widespread attention in cancer
treatment due to its smaller surgical trauma, better selectivity towards tumor cells, reduced …

Activatable self-assembled organic nanotheranostics: Aspartyl aminopeptidase triggered NIR fluorescence imaging-guided photothermal/photodynamic synergistic …

C Zhao, W Liu, W Sun, H Yu, Z Sheng, J Wang… - Analytica Chimica …, 2022 - Elsevier
Phototherapy has developed as a powerful method for remedial modalities. The
conventional photosensitizers are “always on” state and lack tumor targeting, which …

Beyond mouse cancer models: Three-dimensional human-relevant in vitro and non-mammalian in vivo models for photodynamic therapy

M Kucinska, M Murias, P Nowak-Sliwinska - Mutation Research/Reviews in …, 2017 - Elsevier
The proper design of experiments is a critical step for each study in order to obtain
reproducible and reliable data. Taking into account constant competitiveness in the quickly …