Serological testing is a powerful tool in epidemiological studies for understanding viral
circulation and assessing the effectiveness of virus control measures, as is the case of SARS …

For patients with metastatic prostate cancer, the 5-year survival rate of 31% points to a need
for novel therapies and improvement of existing modalities. We propose that p53 gene …

Previously, the authors developed an adenoviral vector, Ad-PG, where transgene
expression is regulated by a p53-responsive promoter. When used to transfer the p53 cDNA …

Balancing safety and efficacy is a major consideration for cancer treatments, especially
when combining cancer immunotherapy with other treatment modalities such as …

Alternative treatments for cancer using gene therapy approaches have shown promising
results and some have even reached the marketplace. Even so, additional improvements …

Here we present the application of our adeno-associated virus (AAV2) vector where
transgene expression is driven by a synthetic, p53-responsive promoter, termed PG, used to …

While cancer immunotherapy has gained much deserved attention in recent years, many
areas regarding the optimization of such modalities remain unexplored, including the …

Tumor vasculature plays a central role in tumor progression, making it an attractive
therapeutic target. In this study, we explore the antiangiogenic potential of our melanoma …

Alloy solidification is a two stage process, which starts by nucleation and ends by growth of
solid phases. Subsequently, number, distribution and morphology (dendritic or nondendritic) …

Immunotherapy of cancer has deservedly gained much attention in the past few years and is
likely to continue to advance and become a fundamental cancer treatment. While vaccines …