Thyrotoxicosis can lead to thyrotoxic periodic paralysis (TPP), an endocrine channelopathy,
and is the most common cause of acquired periodic paralysis. Typically, paralytic attacks …

Thyrotoxic hypokalemic periodic paralysis (TPP) is characterized by acute attacks of
weakness, hypokalemia, and thyrotoxicosis of various etiologies. These transient attacks …

Ion channels serve diverse cellular functions, mainly in cell signal transduction. In endocrine
cells, these channels play a major role in hormonal secretion, Ca2+-mediated cell signaling …

Objective Thyrotoxic hypokalaemic periodic paralysis (THPP) is an uncommon condition
with intermittent episodes of muscle weakness and occasionally severe paralysis. THPP is a …

Background Mutations in several potassium channel subunits have been associated with
rare forms of atrial fibrillation. In order to explore the role of potassium channels in inherited …

Mutations in CACNA1S (calcium channel, voltage‑dependent, L type, alpha 1S subunit) and
SCN4A (sodium channel, voltage‑gated, type IV, alpha subunit) are associated with …

Recognizing the underlying causes of hypokalemic paralysis seems to be essential for the
appropriate management of affected patients and their prevention of recurrent attacks. There …

Background Genetic predisposition has been suggested to play role in the pathogenesis of
thyrotoxic hypokalaemic periodic paralysis (THPP). Objectives In this study, we assessed the …

Study design: Case report. Setting: Temple University Children's Medical Center in USA.
Objectives: To report a patient whose recurrent and transient episodes of quadriplegia …

Resultados: la edad promedio al diagnóstico fue de 35.77±9.6 años, todos de raza mestiza,
en 82% de los pacientes el diagnóstico de hipertiroidismo fue establecido a partir de esta …