Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Engineering bioinks for 3D bioprinting

G Decante, JB Costa, J Silva-Correia, MN Collins… - …, 2021 - iopscience.iop.org
In recent years, three-dimensional (3D) bioprinting has attracted wide research interest in
biomedical engineering and clinical applications. This technology allows for unparalleled …

[HTML][HTML] Polymeric biomaterials for 3D printing in medicine: An overview

R Pugliese, B Beltrami, S Regondi, C Lunetta - Annals of 3D Printed …, 2021 - Elsevier
Abstract Three-dimensional (3D) printing is becoming a booming technology to fabricate
scaffolds, orthoses, and prosthetic devices for tissue engineering, regenerative medicine …

Hydrogel-based fiber biofabrication techniques for skeletal muscle tissue engineering

M Volpi, A Paradiso, M Costantini… - ACS Biomaterials …, 2022 - ACS Publications
The functional capabilities of skeletal muscle are strongly correlated with its well-arranged
microstructure, consisting of parallelly aligned myotubes. In case of extensive muscle loss …

Recent advances on cell culture platforms for in vitro drug screening and cell therapies: from conventional to microfluidic strategies

BD Cardoso, EMS Castanheira… - Advanced …, 2023 - Wiley Online Library
The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …

[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development

AG Monteduro, S Rizzato, G Caragnano… - Biosensors and …, 2023 - Elsevier
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …

Recent advances of organ-on-a-chip in cancer modeling research

X Liu, Q Su, X Zhang, W Yang, J Ning, K Jia, J Xin, H Li… - Biosensors, 2022 - mdpi.com
Although many studies have focused on oncology and therapeutics in cancer, cancer
remains one of the leading causes of death worldwide. Due to the unclear molecular …

3D-bioprinted cancer-on-a-chip: level-up organotypic in vitro models

MV Monteiro, YS Zhang, VM Gaspar, JF Mano - Trends in biotechnology, 2022 - cell.com
Combinatorial conjugation of organ-on-a-chip platforms with additive manufacturing
technologies is rapidly emerging as a disruptive approach for upgrading cancer-on-a-chip …

An insight on advances and applications of 3d bioprinting: A review

AM Bejoy, KN Makkithaya, BB Hunakunti, A Hegde… - Bioprinting, 2021 - Elsevier
Over recent decades, three-dimensional (3D) bioprinting has been studied, improved, and
extensively applied to various areas such as medicine, healthcare, food technology, etc …

Heterotypic tumor spheroids: a platform for nanomedicine evaluation

F Vakhshiteh, Z Bagheri, M Soleimani… - Journal of …, 2023 - Springer
Nanomedicine has emerged as a promising therapeutic approach, but its translation to the
clinic has been hindered by the lack of cellular models to anticipate how tumor cells will …