Mitochondrial membrane permeabilization in cell death

G Kroemer, L Galluzzi, C Brenner - Physiological reviews, 2007 - journals.physiology.org
Irrespective of the morphological features of end-stage cell death (that may be apoptotic,
necrotic, autophagic, or mitotic), mitochondrial membrane permeabilization (MMP) is …

Orthobunyaviruses: recent genetic and structural insights

RM Elliott - Nature Reviews Microbiology, 2014 - nature.com
Orthobunyaviruses, which have small, tripartite, negative-sense RNA genomes and
structurally simple virions composed of just four proteins, can have devastating effects on …

Recent advances in the molecular and cellular biology of bunyaviruses

CT Walter, JN Barr - Journal of General Virology, 2011 - microbiologyresearch.org
The family Bunyaviridae of segmented, negative-stranded RNA viruses includes over 350
members that infect a bewildering variety of animals and plants. Many of these bunyaviruses …

NSm protein of Rift Valley fever virus suppresses virus-induced apoptosis

S Won, T Ikegami, CJ Peters, S Makino - Journal of virology, 2007 - Am Soc Microbiol
Rift Valley fever virus (RVFV) is a member of the genus Phlebovirus within the family
Bunyaviridae. It can cause severe epidemics among ruminants and fever, myalgia, a …

The ORF3 protein of porcine circovirus type 2 is involved in viral pathogenesis in vivo

J Liu, I Chen, Q Du, H Chua, J Kwang - Journal of virology, 2006 - Am Soc Microbiol
ABSTRACT Porcine circovirus type 2 (PCV2) is the primary causative agent of an emerging
swine disease, postweaning multisystemic wasting syndrome. We previously showed that a …

Arboviral encephalitides: transmission, emergence, and pathogenesis

BS Hollidge, F González-Scarano… - Journal of neuroimmune …, 2010 - Springer
Arthropod-borne viruses (arboviruses) are of paramount concern as a group of pathogens at
the forefront of emerging and re-emerging diseases. Although some arboviral infections are …

A Look into Bunyavirales Genomes: Functions of Non-Structural (NS) Proteins

SS Leventhal, D Wilson, H Feldmann, DW Hawman - Viruses, 2021 - mdpi.com
In 2016, the Bunyavirales order was established by the International Committee on
Taxonomy of Viruses (ICTV) to incorporate the increasing number of related viruses across …

La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts

G Blakqori, S Delhaye, M Habjan, CD Blair… - Journal of …, 2007 - Am Soc Microbiol
La Crosse virus (LACV) is a mosquito-transmitted member of the Bunyaviridae family that
causes severe encephalitis in children. For the LACV nonstructural protein NSs, previous …

The non-structural protein of Crimean-Congo hemorrhagic fever virus disrupts the mitochondrial membrane potential and induces apoptosis

B Barnwal, H Karlberg, A Mirazimi, YJ Tan - Journal of Biological Chemistry, 2016 - ASBMB
Viruses have developed distinct strategies to overcome the host defense system. Regulation
of apoptosis in response to viral infection is important for virus survival and dissemination …

Discovery of a unique novel clade of mosquito-associated bunyaviruses

M Marklewitz, F Zirkel, IB Rwego, H Heidemann… - Journal of …, 2013 - Am Soc Microbiol
Bunyaviruses are the largest known family of RNA viruses, infecting vertebrates, insects, and
plants. Here we isolated three novel bunyaviruses from mosquitoes sampled in Côte …