Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that
starts from the genomic sequence of the pathogen and ends with a list of potential protein …

There has been a significant reduction in annual tuberculosis incidence since the World
Health Organization declared tuberculosis a global health threat. However, treatment of M …

Brucella spp. are Gram-negative, facultative intracellular bacteria that cause brucellosis in
humans and various animals. The threat of brucellosis has increased, yet currently available …

Corynebacterium pseudotuberculosis is the etiologic agent of veterinary relevance
diseases, such as caseous lymphadenitis, affecting different animal species causing …

The emergence of multidrug-resistant Corynebacterium jeikeium has limited treatment
options and resulted in the inability to treat C. jeikeium infections, especially in …

Visceral leishmaniasis (VL) is a dreadful protozoan disease caused by Leishmania
donovani that severely affects huge populations in tropical and sub-tropical regions. The …

Caseous lymphadenitis (CLA) is a chronic disease responsible for significant economic
losses in sheep and goat breeding worldwide. The treatment for this disease is not effective …

The advent of effective drug regimen and BCG vaccine has significantly decreased the rate
of morbidity and mortality of TB. However, lengthy treatment and slower recovery rate, as …

Purpose. We tested the efficacy of the esterase encoded by cp1002_RS09720 from
Corynebacterium pseudotuberculosis in recombinant subunit and DNA caseous …

The discovery of novel antigens is an essential requirement in devising new diagnostics or
vaccines for use in control programmes against human tuberculosis (TB) and bovine …