A global perspective on the issue of access to insulin

D Beran, M Lazo-Porras, CM Mba, JC Mbanya - Diabetologia, 2021 - Springer
The discovery of insulin in 1921 changed the prognosis for people with type 1 diabetes. A
century later, availability and affordability of insulin remain a challenge in many parts of the …

Constraints and challenges in access to insulin: a global perspective

D Beran, M Ewen, R Laing - The lancet Diabetes & endocrinology, 2016 - thelancet.com
Substantial attention has been given to the issue of access to medicines for communicable
diseases; however, access to essential medicines for diabetes, especially insulin, has had …

Factors contributing to the rising national cost of glucose-lowering medicines for diabetes during 2005–2007 and 2015–2017

X Zhou, SS Shrestha, H Shao, P Zhang - Diabetes Care, 2020 - Am Diabetes Assoc
OBJECTIVE We examined changes in glucose-lowering medication spending and
quantified the magnitude of factors that are contributing to these changes. RESEARCH …

Production costs and potential prices for biosimilars of human insulin and insulin analogues

D Gotham, MJ Barber, A Hill - BMJ global health, 2018 - gh.bmj.com
Introduction High prices for insulin pose a barrier to treatment for people living with diabetes,
with an estimated 50% of 100 million patients needing insulin lacking reliable access. As …

Patents and regulatory exclusivities on FDA-approved insulin products: A longitudinal database study, 1986–2019

A Olsen, RF Beall, RP Knox, SS Tu… - Plos …, 2023 - journals.plos.org
Background Insulin is the primary treatment for type 1 and some type 2 diabetes but remains
costly in the United States, even though it was discovered more than a century ago. High …

Why are we failing to address the issue of access to insulin? A national and global perspective

D Beran, IB Hirsch, JS Yudkin - Diabetes Care, 2018 - Am Diabetes Assoc
Insulin was discovered in 1921 and soon became widely available in high-income countries.
However, many people currently in need of this life-saving medicine are unable to access it …

Estimated sustainable cost-based prices for diabetes medicines

MJ Barber, D Gotham, H Bygrave… - JAMA Network …, 2024 - jamanetwork.com
Importance The burden of diabetes is growing worldwide. The costs associated with
diabetes put substantial pressure on patients and health budgets, especially in low-and …

[PDF][PDF] Keeping the 100-year-old promise: making insulin access universal

World Health Organization - 2021 - apps.who.int
Executive summary The year 2021 marks 100 years since the momentous discovery of
insulin in 1921, which marked a turning point in care for those with diabetes mellitus …

Is patent “evergreening” restricting access to medicine/device combination products?

RF Beall, JW Nickerson, WA Kaplan, A Attaran - PLoS One, 2016 - journals.plos.org
Background Not all new drug products are truly new. Some are the result of marginal
innovation and incremental patenting of existing products, but in such a way that confers no …

Insulin prices, availability and affordability: a cross-sectional survey of pharmacies in Hubei Province, China

C Liu, X Zhang, C Liu, M Ewen, Z Zhang… - BMC health services …, 2017 - Springer
Background Poor access to affordable insulin results in serious and needless complications
and premature deaths for those with diabetes who need this essential medicine. To help …