Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Forest trees are a major source of biogenic volatile organic compounds (BVOCs). Terpenes
and terpenoids are known as the main BVOCs of forest aerosols. These compounds have …

Cannabaceae plants Cannabis sativa L. and Humulus lupulus L. are rich in terpenes–both
are typically comprised of terpenes as up to 3–5% of the dry-mass of the female …

β-Caryophyllene (BCP), a natural bicyclic sesquiterpene, is a selective phytocannabinoid
agonist of type 2 receptors (CB2-R). It isn't psychogenic due to the absence of an affinity to …

Redox dysfunctions and neuro-oxidative stress play a major role in the pathophysiology and
progression of Parkinson's disease (PD). Glutathione (GSH) and the reduced/oxidized …

Microglia are the most abundant immune cells in the central nervous system (CNS), where
they interact with neurons and exhibit a wide array of functions in physiological and …

In recent years, natural products, which originate from plants, animals, and fungi, together
with their bioactive compounds have been intensively explored and studied for their …

(E)-β-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant
kingdom, where it contributes a unique aroma to essential oils and has a pivotal role in the …

Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …

The discovery of the central role played by the protein alpha-synuclein in Parkinson's
disease and other Lewy body brain disorders has had a great relevance in the …