Eicosanoid signaling in insect immunology: new genes and unresolved issues

Y Kim, D Stanley - Genes, 2021 - mdpi.com
This paper is focused on eicosanoid signaling in insect immunology. We begin with
eicosanoid biosynthesis through the actions of phospholipase A2, responsible for …

The emerging importance of METTL5-mediated ribosomal RNA methylation

EM Turkalj, C Vissers - Experimental & molecular medicine, 2022 - nature.com
The study of the epitranscriptome has thus far focused largely on mRNA methylation. Recent
human genetics studies suggest that methylation of ribosomal RNA also contributes to brain …

Biosynthetic pathway of arachidonic acid in Spodoptera exigua in response to bacterial challenge

MA Hasan, S Ahmed, Y Kim - Insect biochemistry and molecular biology, 2019 - Elsevier
Eicosanoids play crucial roles in mediating insect immune responses. In vertebrates,
phospholipase A 2 (PLA 2) releases arachidonic acid (AA) from phospholipids (PLs) for …

Fat Quality Impacts the Effect of a High-Fat Diet on the Fatty Acid Profile, Life History Traits and Gene Expression in Drosophila melanogaster

V Eickelberg, G Rimbach, Y Seidler, M Hasler, S Staats… - Cells, 2022 - mdpi.com
Feeding a high-fat diet (HFD) has been shown to alter phenotypic and metabolic parameters
in Drosophila melanogaster. However, the impact of fat quantity and quality remains …

Immune Response of Drosophila suzukii Larvae to Infection with the Nematobacterial Complex Steinernema carpocapsae–Xenorhabdus nematophila

A Garriga, M Mastore, A Morton, F Garcia del Pino… - Insects, 2020 - mdpi.com
Entomopathogenic nematodes have been proposed as biological agents for the control of
Drosophila suzukii, an invasive pest of small-stone and soft-skinned fruits. Larvae of the fly …

Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster

P Azizpor, OK Okakpu, SC Parks, D Chavez… - Journal of Lipid …, 2024 - jlr.org
Eicosanoids are a class of molecules derived from C20 polyunsaturated fatty acids (PUFAs)
that play a vital role in mammalian and insect biological systems, including development …

Drosophilamelanogaster Responses against Entomopathogenic Nematodes: Focus on Hemolymph Clots

A Dziedziech, S Shivankar, U Theopold - Insects, 2020 - mdpi.com
Several insect innate immune mechanisms are activated in response to infection by
entomopathogenic nematodes (EPNs). In this review, we focus on the coagulation of …

The first report of prostacyclin and its physiological roles in insects

S Ahmed, MA Al Baki, J Lee, DY Seo, D Lee… - General and …, 2021 - Elsevier
Prostaglandins (PGs) mediate physiological processes of insects as well as mammals.
Prostaglandin I 2 (PGI 2) is a relatively well-known eicosanoid with potent hormone-like …

Aspirin inhibition of prostaglandin synthesis impairs mosquito egg development

D Choi, MA Al Baki, S Ahmed, Y Kim - Cells, 2022 - mdpi.com
Several endocrine signals mediate mosquito egg development, including 20-
hydroxyecdysone (20E). This study reports on prostaglandin E2 (PGE2) as an additional, but …

Prostaglandin D2 synthase and its functional association with immune and reproductive processes in a lepidopteran insect, Spodoptera exigua

SM Sajjadian, S Ahmed, MA Al Baki, Y Kim - General and comparative …, 2020 - Elsevier
Several prostaglandins (PGs) have been identified in different insect species. However, their
biosynthesis and physiological roles in insects remain unclear. PGD 2 is synthesized by …