Near infrared (NIR) light utilization in a range of current technologies has gained huge
significance due to its abundance in nature and nondestructive properties. NIR active …

Confirming the direct link between neural circuit activity and animal behavior has been a
principal aim of neuroscience. The genetically encoded calcium indicator (GECI), which …

We developed a new method for the conditional regulation of CRISPR/Cas9 activity in
mammalian cells and zebrafish embryos using photochemically activated, caged guide …

A robust method for simultaneous visualization of all four cell cycle phases in living cells is
highly desirable. We developed an intensiometric reporter of the transition from S to G2 …

Industrial fermentation processes strive for high robustness to ensure optimal and consistent
performance. Medium components, fermentation products, and physical perturbations may …

In previous work, we showed that intrinsically disordered regions (IDRs) of proteins contain
sequence-distributed molecular features that are conserved over evolution, despite little …

Fluorescent proteins (FPs) are indispensable tools used for molecular imaging, single-cell
dynamics, imaging in infection models, and more. However, next-generation FPs have yet to …

The general interest in microbial ecology has skyrocketed over the past decade, driven by
technical advances and by the rapidly increasing appreciation of the fundamental services …

Molecular signals interact in networks to mediate biological processes. To analyze these
networks, it would be useful to image many signals at once, in the same living cell, using …

Förster resonance energy transfer (FRET) microscopy is a powerful fluorescence
microscopy method to study the nanoscale organization of multiprotein assemblies in vivo …