COVID-19 and cardiovascular disease: from bench to bedside
A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential
consequences on the cardiovascular health of millions of people who survive infection …
consequences on the cardiovascular health of millions of people who survive infection …
Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities
LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β-Cells and in the Human Pancreas Microvasculature
Increasing evidence demonstrated that the expression of Angiotensin I-Converting Enzyme
type 2 (ACE2) is a necessary step for SARS-CoV-2 infection permissiveness. In light of the …
type 2 (ACE2) is a necessary step for SARS-CoV-2 infection permissiveness. In light of the …
RGD-binding integrins revisited: how recently discovered functions and novel synthetic ligands (re-) shape an ever-evolving field
Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …
investigated as therapeutic targets over the last decades, motivated by their multiple …
COVID-19 and the vasculature: current aspects and long-term consequences
B Martinez-Salazar, M Holwerda, C Stuedle… - Frontiers in cell and …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …
December 2019 as a novel respiratory pathogen and is the causative agent of Corona Virus …
[HTML][HTML] Interaction of SARS-CoV-2 with cardiomyocytes: Insight into the underlying molecular mechanisms of cardiac injury and pharmacotherapy
A Abdi, S AlOtaiby, F Al Badarin, A Khraibi… - Biomedicine & …, 2022 - Elsevier
SARS-CoV-2 causes respiratory illness with a spectrum of systemic complications. However,
the mechanism for cardiac infection and cardiomyocyte injury in COVID-19 patients remains …
the mechanism for cardiac infection and cardiomyocyte injury in COVID-19 patients remains …
SARS-CoV-2 Infects Human ACE2-Negative Endothelial Cells through an αvβ3 Integrin-Mediated Endocytosis Even in the Presence of Vaccine-Elicited Neutralizing …
A Bugatti, F Filippini, M Bardelli, A Zani, P Chiodelli… - Viruses, 2022 - mdpi.com
Integrins represent a gateway of entry for many viruses and the Arg-Gly-Asp (RGD) motif is
the smallest sequence necessary for proteins to bind integrins. All Severe Acute Respiratory …
the smallest sequence necessary for proteins to bind integrins. All Severe Acute Respiratory …
[HTML][HTML] Factors modulating COVID-19: A mechanistic understanding based on the adverse outcome pathway framework
Addressing factors modulating COVID-19 is crucial since abundant clinical evidence shows
that outcomes are markedly heterogeneous between patients. This requires identifying the …
that outcomes are markedly heterogeneous between patients. This requires identifying the …
Cell surface detection of vimentin, ACE2 and SARS-CoV-2 Spike proteins reveals selective colocalization at primary cilia
V Lalioti, S González-Sanz, I Lois-Bermejo… - Scientific reports, 2022 - nature.com
Abstract The SARS-CoV-2 Spike protein mediates docking of the virus onto cells prior to
viral invasion. Several cellular receptors facilitate SARS-CoV-2 Spike docking at the cell …
viral invasion. Several cellular receptors facilitate SARS-CoV-2 Spike docking at the cell …
COVID-19-related cardiac complications from clinical evidences to basic mechanisms: opinion paper of the ESC Working Group on Cellular Biology of the Heart
The pandemic of coronavirus disease (COVID)-19 is a global threat, causing high mortality,
especially in the elderly. The main symptoms and the primary cause of death are related to …
especially in the elderly. The main symptoms and the primary cause of death are related to …