Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Feeding provides substrate for energy metabolism, which is vital to the survival of every
living animal and therefore is subject to intense regulation by brain homeostatic and hedonic …

Why does performing certain tasks cause the aversive experience of mental effort and
concomitant deterioration in task performance? One explanation posits a physical resource …

Ghrelin, an appetite-stimulatory hormone secreted by the stomach, was discovered as a
ligand for the growth hormone secretagogue receptor (GHSR). Through GHSR, ghrelin …

Genetic variants responsible for susceptibility to obesity and its comorbidities among
Hispanic children have not been identified. The VIVA LA FAMILIA Study was designed to …

Abstract The melanocortin-4 receptor (MC4R) is critically involved in regulating energy
balance, and obesity has been observed in mice with mutations in the gene for brain …

Internal physiological states influence behavioral decisions. We have investigated the
underlying cellular and molecular mechanisms at the first olfactory synapse for starvation …

Obesity is an important cause of morbidity and mortality in developed countries, and is also
becoming increasingly prevalent in the developing world. Although environmental factors …

Kisspeptin is a neuropeptide with a critical role in the function of the hypothalamic–pituitary–
gonadal (HPG) axis. Kisspeptin is produced by two major populations of neurons located in …

Dietary protein enhances satiety and promotes weight loss, but the mechanisms by which
appetite is affected remain unclear. We investigated the role of gut hormones, key regulators …