Chemokines, which are basic proteins that exert their effects via G protein-coupled receptors
and a subset of the cytokine family, are mediators deeply involved in leukocyte migration …

Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …

Psoriasis is a TNF‐α/IL‐23/IL‐17A–mediated inflammatory skin disease that causes a
significant socioeconomic burden in afflicted patients. IL‐17A–producing immune cells …

The CC chemokine receptor 6 (CCR6) is a G protein-coupled receptor (GPCR) involved in a
wide range of biological processes. When CCR6 binds to its sole ligand CCL20, a signaling …

Purpose Benefit from convalescent plasma therapy for coronavirus disease 2019 (COVID-
19) has been inconsistent in randomized clinical trials (RCTs) involving critically ill patients …

CCL20, as a chemokine, plays an important role in rheumatoid arthritis, psoriasis, and other
diseases by binding to its receptor CCR6. Recent 10 years' research has demonstrated that …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
worldwide pandemic, infecting over 16 million people worldwide with a significant mortality …

Systemic lupus erythematosus (SLE), a common autoimmune disease with a global
incidence and newly diagnosed population estimated at 5.14 (range, 1.4‑15.13) per 100,000 …

Background Lung adenocarcinoma (LUAD) is the most common type of lung cancer with a
high incidence and increased mortality. CC chemokine receptors were participating in the …

The alpha-Gal syndrome (AGS) is associated with tick bites that can induce in humans high
levels of IgE antibodies against the carbohydrate Galα1-3Galβ1-(3) 4GlcNAc-R (α-Gal) …