Developmental and functional heterogeneity of monocytes

M Guilliams, A Mildner, S Yona - Immunity, 2018 - cell.com
Novel experimental approaches such as fate-mapping and single-cell analysis have brought
fresh insight into monocyte development and function over the past decade and helped …

Genetic models of human and mouse dendritic cell development and function

DA Anderson III, CA Dutertre, F Ginhoux… - Nature Reviews …, 2021 - nature.com
Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have
numerous shared characteristics between mice and humans. Human counterparts of mouse …

Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors

Z Liu, H Wang, Z Li, RJ Dress, Y Zhu, S Zhang… - Immunity, 2023 - cell.com
Conventional dendritic cells (cDCs) are professional antigen-presenting cells that control the
adaptive immune response. Their subsets and developmental origins have been intensively …

Human dendritic cell subsets: an update

M Collin, V Bigley - Immunology, 2018 - Wiley Online Library
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Plasmacytoid dendritic cells: development, regulation, and function

B Reizis - Immunity, 2019 - cell.com
Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-
derived nucleic acids and respond with rapid and massive production of type I interferon …

Antigen presentation by dendritic cells and their instruction of CD4+ T helper cell responses

KL Hilligan, F Ronchese - Cellular & molecular immunology, 2020 - nature.com
Dendritic cells are powerful antigen-presenting cells that are essential for the priming of T
cell responses. In addition to providing T-cell-receptor ligands and co-stimulatory molecules …

Functions of murine dendritic cells

V Durai, KM Murphy - Immunity, 2016 - cell.com
Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating
adaptive immune responses. The functions of DCs were originally obscured by their overlap …

Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells

PF Rodrigues, L Alberti-Servera, A Eremin… - Nature …, 2018 - nature.com
Plasmacytoid dendritic cells (pDCs) are an immune subset devoted to the production of high
amounts of type 1 interferons in response to viral infections. Whereas conventional dendritic …

The cytokine TGF-β promotes the development and homeostasis of alveolar macrophages

X Yu, A Buttgereit, I Lelios, SG Utz, D Cansever… - Immunity, 2017 - cell.com
Alveolar macrophages (AMs) derive from fetal liver monocytes, which colonize the lung
during embryonic development and give rise to fully mature AMs perinatally. AM …

Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species

M Guilliams, CA Dutertre, CL Scott, N McGovern… - Immunity, 2016 - cell.com
Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic
potential. Multiple DC subsets have been described, and it remains challenging to align …