The arginase enzyme developed in early life forms and was maintained during evolution. As
the last step in the urea cycle, arginase cleaves l-arginine to form urea and l-ornithine. The …

Arginase has roots in early life-forms. It converts L-arginine to urea and ornithine. The former
provides protection against NH 3; the latter serves to stimulate cell growth and other …

The pathological characteristics of atherosclerosis (AS) include lipid accumulation, fibrosis
formation and atherosclerotic plaque produced in artery intima, which leads to vascular …

Arginase, a binuclear manganese metalloenzyme in the urea, catalyzes the hydrolysis of L-
arginine to urea and L-ornithine. Both isoforms, arginase 1 and arginase 2 perform …

Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the retina and a leading
cause of visual impairment and childhood blindness worldwide. The disease is …

The understanding, diagnosis, and treatment of retinopathy of prematurity have changed in
the 70 years since the original description of retrolental fibroplasia associated with high …

Abstract Arginase (EC 3.5. 3.1) is the bimanganese enzyme that converts L‐arginine into
ornithine and urea. This enzyme was discovered more than a century ago and early α …

Atherosclerosis and its clinical complications constitute the major healthcare problems of the
world population. Due to the central role of endothelium throughout the atherosclerotic …

During the perinatal period, free radicals (FRs) are involved in several physiological roles
such as the cellular responses to noxia, the defense against infectious agents, the regulation …

Retinopathy of prematurity (ROP) is a retinal vasoproliferative disorder that represents an
important cause of childhood visual impairment and blindness. Although oxidative stress …