Metastatic dissemination of solid tumors, a leading cause of cancer-related mortality,
underscores the urgent need for enhanced insights into the molecular and cellular …

Simple Summary Mutational hotspots have gained importance as oncological biomarkers in
recent years because of their potential as predictors of clinical outcomes and/or therapeutic …

Abstract Background Antibody–drug conjugates (ADCs) enhance the specificity of cytotoxic
drugs by directing them to cells expressing target antigens. Multiple ADCs are FDA …

Abstract Craniopharyngiomas (CPs), particularly Adamantinomatous Craniopharyngiomas
(ACPs), often exhibit a heightened risk of postoperative recurrence and severe …

Context Outcome of craniopharyngioma is related to its locoregional extension, which
impacts resectability and the risk of surgical complications. To maximize resection and …

Objective Craniopharyngioma (CP) is a benign neuroepithelial tumor generally treated with
maximal safe resection and radiation therapy (RT) in incompletely resected CP or in …

Craniopharyngiomas present unique challenges in surgical management due to their
proximity to critical neurovascular structures. This systematic review investigates genetic and …

Papillary craniopharyngiomas are ultra-rare tumors of the central nervous system (CNS),
with fewer than 600 new cases per year in the United States. These tumors most commonly …

Opinion statement The integration of targeted therapy into the multimodal management of
craniopharyngiomas represents a significant advancement in the field of neuro-oncology …

Introduction Numerous studies have demonstrated Fractionated Stereotactic Radiotherapy's
(FSRT) effectiveness in tumor control post-resection for craniopharyngiomas. Nevertheless …