Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?

EJ Villablanca, K Selin, CRH Hedin - Nature Reviews Gastroenterology …, 2022 - nature.com
Almost all currently available treatments for inflammatory bowel disease (IBD) act by
inhibiting inflammation, often blocking specific inflammatory molecules. However, given the …

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

ECCO guidelines on therapeutics in ulcerative colitis: medical treatment

T Raine, S Bonovas, J Burisch… - Journal of Crohn's …, 2022 - academic.oup.com
Ulcerative colitis [UC] is a chronic inflammatory bowel disease [IBD] characterised by colonic
inflammation extending to a variable extent from the rectum. Care of the patient with UC …

ECCO guidelines on therapeutics in Crohn's disease: medical treatment

J Torres, S Bonovas, G Doherty… - Journal of Crohn's …, 2020 - academic.oup.com
2. Methods Based on the GRADE workflow, the Guidelines Committee of ECCO [GuiCom]
selected a panel of 48 experts supported by a team of methodologists and librarians …

Oxidative stress and redox-modulating therapeutics in inflammatory bowel disease

AR Bourgonje, M Feelisch, KN Faber, A Pasch… - Trends in molecular …, 2020 - cell.com
Inflammatory bowel disease (IBD) is associated with the production of reactive species that
target cysteine redox switches in proteins, thereby affecting gene regulation, DNA damage …

Dietary management of adults with IBD—the emerging role of dietary therapy

JA Fitzpatrick, SL Melton, CK Yao, PR Gibson… - Nature Reviews …, 2022 - nature.com
Historically, dietitians played a minor part in the management of inflammatory bowel disease
(IBD), including Crohn's disease and ulcerative colitis. Patients were commonly referred for …

ECCO guidelines on therapeutics in Crohn's disease: surgical treatment

M Adamina, S Minozzi, J Warusavitarne… - Journal of Crohn's …, 2024 - academic.oup.com
This article is the second in a series of two publications on the European Crohn's and Colitis
Organisation [ECCO] evidence-based consensus on the management of Crohn's disease …

Faecal microbiota transplantation with anti-inflammatory diet (FMT-AID) followed by anti-inflammatory diet alone is effective in inducing and maintaining remission …

S Kedia, S Virmani, SK Vuyyuru, P Kumar, B Kante… - Gut, 2022 - gut.bmj.com
Objective Microbiome and dietary manipulation therapies are being explored for treating
ulcerative colitis (UC). We aimed to examine the efficacy of multidonor faecal microbiota …

Food additive emulsifiers and their impact on gut microbiome, permeability, and inflammation: mechanistic insights in inflammatory bowel disease

AS Bancil, AM Sandall, M Rossi… - Journal of Crohn's …, 2021 - academic.oup.com
The global burden of inflammatory bowel disease [IBD] has increased over the 21st century.
Despite multiple studies investigating the pathogenesis of IBD, the causative mechanisms …

The role of dietary nutrients in inflammatory bowel disease

K Sugihara, TL Morhardt, N Kamada - Frontiers in immunology, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disease of the
gastrointestinal tract. Although the precise etiology of IBD remains incompletely understood …