[HTML][HTML] Stress and telomere shortening: Insights from cellular mechanisms

J Lin, E Epel - Ageing research reviews, 2022 - Elsevier
Short telomeres confer risk of degenerative diseases. Chronic psychological stress can lead
to disease through many pathways, and research from in vitro studies to human longitudinal …

Association between genetically determined telomere length and health‐related outcomes: A systematic review and meta‐analysis of Mendelian randomization …

B Chen, Y Yan, H Wang, J Xu - Aging Cell, 2023 - Wiley Online Library
Emerging evidence has shown that leukocyte telomere length (LTL) is associated with
various health‐related outcomes, while the causality of these associations remains unclear …

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

F Morales Berstein, DL McCartney, AT Lu, KK Tsilidis… - Elife, 2022 - elifesciences.org
Background: Epigenetic clocks have been associated with cancer risk in several
observational studies. Nevertheless, it is unclear whether they play a causal role in cancer …

Telomere length changes in cancer: insights on carcinogenesis and potential for non-invasive diagnostic strategies

Z Holesova, L Krasnicanova, R Saade, O Pös, J Budis… - Genes, 2023 - mdpi.com
Telomere dynamics play a crucial role in the maintenance of chromosome integrity; changes
in telomere length may thus contribute to the development of various diseases including …

Mendelian randomization study on the causal relationship between leukocyte telomere length and prostate cancer

B Wan, L Lu, C Lv - PLoS One, 2023 - journals.plos.org
Background Leukocyte telomere length (LTL) is related to prostate cancer (PCa). However,
the causal relationship between them remains unknown. This study was aimed at identifying …

Family socioeconomic status and child telomere length among the Samburu of Kenya

BL Needham, B Straight, CE Hilton, CO Olungah… - Social Science & …, 2021 - Elsevier
Previous research in high-income countries suggests that children from families with lower
socioeconomic status (SES) tend to have shorter telomere length–a biomarker of stress and …

Investigating the influence of breastfeeding on asthma in children under 12 years old in the UK Biobank

W Hou, F Guan, L Xia, Y Xu, S Huang… - Frontiers in …, 2022 - frontiersin.org
Background Childhood-onset asthma (COA) has become a major and growing problem
worldwide and imposes a heavy socioeconomic burden on individuals and families; …

Incorporating genetic similarity of auxiliary samples into eGene identification under the transfer learning framework

S Zhang, Z Jiang, P Zeng - Journal of Translational Medicine, 2024 - Springer
Background The term eGene has been applied to define a gene whose expression level is
affected by at least one independent expression quantitative trait locus (eQTL). It is both …

Predicted leukocyte telomere length and risk of myeloid neoplasms

SM Sullivan, B Cole, J Lane, JJ Meredith… - Human molecular …, 2023 - academic.oup.com
Maintenance of telomere length has long been established to play a role in the biology of
cancer and several studies suggest that it may be especially important in myeloid …

Decoupling blood telomere length from age in recipients of allogeneic hematopoietic cell transplant in the BMT-CTN 1202

TP Lai, S Verhulst, CL Dagnall, A Hutchinson… - Frontiers in …, 2022 - frontiersin.org
The age of allogeneic hematopoietic cell transplant (HCT) donors and their hematopoietic
cell telomere length (TL) might affect recipients' outcomes. Our goals were to examine the …