MiR-137: an important player in neural development and neoplastic transformation

E Mahmoudi, MJ Cairns - Molecular psychiatry, 2017 - nature.com
MicroRNAs (miRNAs) represent an important class of small regulatory RNAs that control
gene expression posttranscriptionally by targeting mRNAs for degradation or translation …

Epigenetics of colorectal cancer

A Goel, CR Boland - Gastroenterology, 2012 - Elsevier
In the early years of the molecular biology revolution, cancer research was mainly focused
on genetic changes (ie, those that altered DNA sequences). Although this has been …

MicroRNA: biogenesis, function and role in cancer

LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …

MicroRNAs: predictors and modifiers of chemo-and radiotherapy in different tumour types

R Hummel, DJ Hussey, J Haier - European journal of cancer, 2010 - Elsevier
MicroRNAs (miRNAs) represent a class of naturally occurring small non-coding RNA
molecules. They regulate gene expression at the post-transcriptional level and control …

MicroRNAs in colorectal cancer: translation of molecular biology into clinical application

O Slaby, M Svoboda, J Michalek, R Vyzula - Molecular cancer, 2009 - Springer
MicroRNAs (miRNAs) are small non-coding RNAs 18-25 nucleotides in length that
downregulate gene expression during various crucial cell processes such as apoptosis …

Micromarkers: miRNAs in cancer diagnosis and prognosis

M Ferracin, A Veronese, M Negrini - Expert review of molecular …, 2010 - Taylor & Francis
Molecular diagnostics in cancer should provide the highest specificity and sensitivity in
classification, prognostic stratification and early detection. miRNAs could contribute to hitting …

MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer

KH Chang, P Mestdagh, J Vandesompele, MJ Kerin… - BMC cancer, 2010 - Springer
Background Advances in high-throughput technologies and bioinformatics have transformed
gene expression profiling methodologies. The results of microarray experiments are often …

[HTML][HTML] miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6

X Zhu, Y Li, H Shen, H Li, L Long, L Hui, W Xu - FEBS letters, 2013 - Elsevier
MicroRNAs (miRNA) have emerged as key players in carcinogenesis. Here, we investigated
the role of miR-137 in the pathogenesis of lung cancer. The downregulation of miR-137 in …

MicroRNAs in colorectal carcinoma-from pathogenesis to therapy

Y Chi, D Zhou - Journal of Experimental & Clinical Cancer Research, 2016 - Springer
Background Acting as inflammatory mediators, tumor oncogenes or suppressors,
microRNAs are involved in cell survival, death, epithelial–mesenchymal transition and …

A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

GDV Scarpati, F Falcetta, C Carlomagno… - International journal of …, 2012 - Elsevier
PURPOSE: MicroRNAs (miRNAs) are small, noncoding RNA molecules that can be down-or
upregulated in colorectal cancer and have been associated to prognosis and response to …