Visualizing structure and transitions in high-dimensional biological data

KR Moon, D Van Dijk, Z Wang, S Gigante… - Nature …, 2019 - nature.com
The high-dimensional data created by high-throughput technologies require visualization
tools that reveal data structure and patterns in an intuitive form. We present PHATE, a …

Hyperbolic diffusion embedding and distance for hierarchical representation learning

YWE Lin, RR Coifman, G Mishne… - … on Machine Learning, 2023 - proceedings.mlr.press
Finding meaningful representations and distances of hierarchical data is important in many
fields. This paper presents a new method for hierarchical data embedding and distance. Our …

Manifold-based nonlocal second-order regularization for hyperspectral image inpainting

J Zheng, J Jiang, H Xu, Z Liu… - IEEE Journal of Selected …, 2020 - ieeexplore.ieee.org
The low-dimensional manifold of image patches has been introduced as regularizer term,
and shown effective in hyperspectral image inpainting. However, in this article, we find that …

Neural FIM for learning Fisher information metrics from point cloud data

O Fasina, G Huguet, A Tong, Y Zhang… - International …, 2023 - proceedings.mlr.press
Although data diffusion embeddings are ubiquitous in unsupervised learning and have
proven to be a viable technique for uncovering the underlying intrinsic geometry of data …

Visualizing structure and transitions for biological data exploration

KR Moon, D Dijk, Z Wang, D Burkhardt… - Available at SSRN …, 2018 - papers.ssrn.com
With the advent of high-throughput technologies measuring high-dimensional biological
data, there is a pressing need for visualization tools that reveal data structure and emergent …

Visualizing transitions and structure for high dimensional data exploration

KR Moon, D van Dijk, Z Wang, D Burkhardt, WS Chen… - bioRxiv, 2017 - biorxiv.org
In the era of 'Big Data'there is a pressing need for tools that provide human interpretable
visualizations of emergent patterns in high-throughput high-dimensional data. Further, to …

On the location of maxima of solutions of Schrödinger's equation

M Rachh, S Steinerberger - Communications on Pure and …, 2018 - Wiley Online Library
We prove an inequality with applications to solutions of the Schrödinger equation. There is a
universal constant c> 0 such that if is simply connected, vanishes on the boundary∂ Ω, and …

Detecting localized eigenstates of linear operators

J Lu, S Steinerberger - Research in the Mathematical Sciences, 2018 - Springer
We describe a way of detecting the location of localized eigenvectors of the eigenvalue
problem Ax= λ x A x= λ x for eigenvalues λ λ with| λ|| λ| comparatively large. We define the …

A metric on directed graphs and markov chains based on hitting probabilities

ZM Boyd, N Fraiman, J Marzuola, PJ Mucha… - SIAM Journal on …, 2021 - SIAM
The shortest-path, commute time, and diffusion distances on undirected graphs have been
widely employed in applications such as dimensionality reduction, link prediction, and trip …

Automated cellular structure extraction in biological images with applications to calcium imaging data

G Mishne, RR Coifman, M Lavzin, J Schiller - BioRXiv, 2018 - biorxiv.org
Recent advances in experimental methods in neuroscience enable measuring in-vivo
activity of large populations of neurons at cellular level resolution. To leverage the full …