Anticancer activity of natural compounds from plant and marine environment

A Lichota, K Gwozdzinski - International journal of molecular sciences, 2018 - mdpi.com
This paper describes the substances of plant and marine origin that have anticancer
properties. The chemical structure of the molecules of these substances, their properties …

Podophyllotoxin: history, recent advances and future prospects

Z Shah, UF Gohar, I Jamshed, A Mushtaq, H Mukhtar… - Biomolecules, 2021 - mdpi.com
Podophyllotoxin, along with its various derivatives and congeners are widely recognized as
broad-spectrum pharmacologically active compounds. Etoposide, for instance, is the …

Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances

F Zálešák, DJYD Bon, J Pospíšil - Pharmacological Research, 2019 - Elsevier
Lignans and neolignans are plant secondary metabolites derived from the oxidative
coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from …

[HTML][HTML] Honokiol: An anticancer lignan

A Rauf, S Patel, M Imran, A Maalik, MU Arshad… - Biomedicine & …, 2018 - Elsevier
Abstract Background Honokiol ((3′, 5-di-(2-propenyl)-1, 1′-biphenyl-2, 2′-diol), a lignan,
is a promising antitumor compound, having exerted activity against a number of human …

An Ethnopharmacological, Phytochemical and Pharmacological Review on Lignans from Mexican Bursera spp.

MC Marcotullio, M Curini, JX Becerra - Molecules, 2018 - mdpi.com
The genus Bursera belongs to the family Burseraceae and has been used in traditional
Mexican medicine for treating various pathophysiological disorders. The most representative …

Junipers of various origins as potential sources of the anticancer drug precursor podophyllotoxin

DI Ivanova, PT Nedialkov, AN Tashev, M Olech… - Molecules, 2021 - mdpi.com
Juniper representatives are natural sources of plenty of bioactive metabolites and have
been used since ancient times as folk remedies against tapeworms, warts, cancer, etc. The …

Juniperus sabina L. as a Source of Podophyllotoxins: Extraction Optimization and Anticholinesterase Activities

S Xu, X Li, S Liu, P Tian, D Li - International Journal of Molecular Sciences, 2022 - mdpi.com
Juniperus sabina L.(J. sabina) has been an important plant in traditional medicine since
ancient times. Its needles are rich in podophyllotoxin, a precursor compound to anti-tumor …

Investigation of Linum flavum (L.) Hairy Root Cultures for the Production of Anticancer Aryltetralin Lignans

S Renouard, C Corbin, S Drouet, B Medvedec… - International journal of …, 2018 - mdpi.com
Linum flavum hairy root lines were established from hypocotyl pieces using Agrobacterium
rhizogenes strains LBA 9402 and ATCC 15834. Both strains were effective for …

Functional characterization of the pinoresinol–lariciresinol reductase-2 gene reveals its roles in yatein biosynthesis and flax defense response

C Corbin, S Drouet, I Mateljak, L Markulin, C Decourtil… - Planta, 2017 - Springer
Main conclusion This study provides new insights into the biosynthesis regulation and in
planta function of the lignan yatein in flax leaves. Pinoresinol–lariciresinol reductases (PLR) …

Anticancer drugs from plants

DFC Moraes, LSS de Mesquita, FMM do Amaral… - … and production of anti …, 2017 - Springer
Cancer is a major problem of public health and one of the main causes of death around the
globe. According to World Health Organization, the prevalence of this disease is rising …