Abstract Information theory (IT) addresses the analysis of communication systems and has
been widely applied in molecular biology. In particular, alignment-free sequence analysis …

Post-Sanger sequencing methods produce tons of data, and there is a generalagreement
that the challenge to store and process them must be addressedwith data compression. In …

Storage and transmission of the data produced by modern DNA sequencing instruments has
become a major concern, which prompted the Pistoia Alliance to pose the …

A repetitive sequence collection is a set of sequences which are small variations of each
other. A prominent example are genome sequences of individuals of the same or close …

Motivation: Modern sequencing instruments are able to generate at least hundreds of
millions short reads of genomic data. Those huge volumes of data require effective means to …

Abstract Motivation: The Burrows–Wheeler transform (BWT) is the foundation of many
algorithms for compression and indexing of text data, but the cost of computing the BWT of …

Research in the genomic sciences is confronted with the volume of sequencing and
resequencing data increasing at a higher pace than that of data storage and communication …

With the rapid development of high-throughput DNA sequencing technologies, the amount
of DNA sequence data is accumulating exponentially. The huge influx of data creates new …

Background Assays of multiple tumor samples frequently reveal recurrent genomic
aberrations, including point mutations and copy-number alterations, that affect individual …

The exponential growth of high-throughput DNA sequence data has posed great challenges
to genomic data storage, retrieval and transmission. Compression is a critical tool to address …