Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor
(NGF) and brain-derived neurotrophic factor (BDNF) are important for the survival …

Neurotrophins and their receptors modulate multiple signalling pathways to regulate
neuronal survival and to maintain axonal and dendritic networks and synaptic plasticity …

There is increasing evidence of prodromal manifestation of neuropsychiatric symptoms in a
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …

Brain‐derived neurotrophic factor (BDNF) is the most studied neurotrophin involved in
synaptic plasticity processes that are required for long‐term learning and memory …

The projected increase in the incidence of dementia in the population highlights the urgent
need for a more comprehensive understanding of how different aspects of lifestyle, in …

Dendritic spines are tiny membrane specialization forming the postsynaptic part of most
excitatory synapses. They have been suggested to play a crucial role in regulating synaptic …

Increasing evidence suggests that reductions in brain-derived neurotrophic factor (BDNF)
and its receptor tyrosine receptor kinase B (TrkB) may have a role in the pathogenesis of …

Synaptic loss in the brain correlates well with disease severity in Alzheimer disease (AD).
Deficits in brain-derived neurotrophic factor/tropomyosin-receptor-kinase B (TrkB) signaling …

During development of the nervous system, the formation of connections (synapses)
between neurons is dependent upon electrical activity in those neurons, and neurotrophic …

Brain-derived neurotrophic factor (BDNF) and its single transmembrane receptor,
tropomysin-related kinase B (TrkB), are essential for adult synaptic plasticity and the …