Tailed bacteriophages with genomes larger than 200 kbp are classified as Jumbo phages,
and are rarely isolated by conventional methods. These phages are designated “jumbo” …

Subcellular organization is essential for life. Cells organize their functions into organelles to
concentrate their machinery and supplies for optimal efficiency. Likewise, viruses organize …

When the process of cell-fate determination is examined at single-cell resolution, it is often
observed that individual cells undergo different fates even when subject to identical …

Nucleic acid synthesis is spatially organized in many organisms. In bacteria, however, the
spatial distribution of transcription remains obscure, owing largely to the diffraction limit of …

The bacteriophages have been explored at a huge scale as a model system for their
applications in many biological-related fields. Jumbo phages with a large genome size from …

Bacteria, like eukaryotes, employ cytoskeletal elements to perform many functions, including
cell morphogenesis, cell division, DNA partitioning, and cell motility. They not only possess …

Tubulins are essential for the reproduction of many eukaryotic viruses, but historically,
bacteriophage were assumed not to require a cytoskeleton. Here, we identify a tubulin-like …

Many eukaryotic viruses assemble mature particles within distinct subcellular compartments,
but bacteriophages are generally assumed to assemble randomly throughout the host cell …

Bacteriophages and their bacterial hosts are ancient organisms that have been co-evolving
for billions of years. Some jumbo phages, those with a genome size larger than 200 …

Nucleus-forming phages (chimalliviruses) encode numerous genes responsible for creating
intricate structures for viral replication. Research on this newly appreciated family of phages …