Exploration of natural compounds with anti-SARS-CoV-2 activity via inhibition of SARS-CoV-2 Mpro
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is a dreaded pandemic in lack of specific …
syndrome coronavirus 2 (SARS-CoV-2), is a dreaded pandemic in lack of specific …
Anticancer peptides prediction with deep representation learning features
Anticancer peptides constitute one of the most promising therapeutic agents for combating
common human cancers. Using wet experiments to verify whether a peptide displays …
common human cancers. Using wet experiments to verify whether a peptide displays …
Bitter-RF: a random forest machine model for recognizing bitter peptides
YF Zhang, YH Wang, ZF Gu, XR Pan, J Li… - Frontiers in …, 2023 - frontiersin.org
Introduction Bitter peptides are short peptides with potential medical applications. The huge
potential behind its bitter taste remains to be tapped. To better explore the value of bitter …
potential behind its bitter taste remains to be tapped. To better explore the value of bitter …
Dengue virus NS4B protein as a target for developing antivirals
Q Li, C Kang - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Dengue virus is an important pathogen affecting global population while no specific
treatment is available against this virus. Effort has been made to develop inhibitors through …
treatment is available against this virus. Effort has been made to develop inhibitors through …
Assessing the inhibitory potential of anti-dengue compounds against Japanese encephalitis virus RNA dependent RNA polymerase: An in silico study
Japanese encephalitis (JE), a neurological infection of severe nature, is caused by the
Japanese encephalitis virus (JEV) and is transmitted by the mosquito vector. The …
Japanese encephalitis virus (JEV) and is transmitted by the mosquito vector. The …
Repositioning of anti-dengue compounds against SARS-CoV-2 as viral polyprotein processing inhibitor
A therapy for COVID-19 (Coronavirus Disease 19) caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) remains elusive due to the lack of an effective …
Syndrome Coronavirus 2 (SARS-CoV-2) remains elusive due to the lack of an effective …
Pharmacophore-model-based drug repurposing for the identification of the potential inhibitors targeting the allosteric site in dengue virus NS5 RNA-dependent RNA …
Dengue virus (DENV) is the causative agent of DENV infection. To tackle DENV infection,
the development of therapeutic molecules as direct-acting antivirals (DAAs) has been …
the development of therapeutic molecules as direct-acting antivirals (DAAs) has been …
Exploration of potent antiviral phytomedicines from lauraceae family plants against SARS-CoV-2 main protease
A new Coronaviridae strain, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-
CoV-2), emerged from Wuhan city of China and caused one of the substantial global health …
CoV-2), emerged from Wuhan city of China and caused one of the substantial global health …
Application of temperature-dependent and steered molecular dynamics simulation to screen anti-dengue compounds against Marburg virus
AA Rabaan, ZH Almansour, A Al Bshabshe… - Journal of …, 2024 - Taylor & Francis
Marburg virus infections are extremely fatal with a fatality range of 23% to 90%, therefore
there is an urgent requirement to design and develop efficient therapeutic molecules. Here …
there is an urgent requirement to design and develop efficient therapeutic molecules. Here …
Ligand-based pharmacophore modeling and QSAR approach to identify potential dengue protease inhibitors
The viral disease dengue is transmitted by the Aedes mosquito and is commonly seen to
occur in the tropical and subtropical regions of the world. It is a growing public health …
occur in the tropical and subtropical regions of the world. It is a growing public health …