IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunity
M Gómez-Herranz, J Taylor, RD Sloan - Journal of Biological Chemistry, 2023 - ASBMB
Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …
Cryo-EM structure of severe fever with thrombocytopenia syndrome virus
The severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne human-
infecting bunyavirus, which utilizes two envelope glycoproteins, Gn and Gc, to enter host …
infecting bunyavirus, which utilizes two envelope glycoproteins, Gn and Gc, to enter host …
Role of Viral Envelope Proteins in Determining Susceptibility of Viruses to IFITM Proteins
T Marceau, M Braibant - Viruses, 2024 - mdpi.com
Interferon-induced transmembrane proteins (IFITMs) are a family of proteins which inhibit
infections of various enveloped viruses. While their general mechanism of inhibition seems …
infections of various enveloped viruses. While their general mechanism of inhibition seems …
IFITM3 inhibits severe fever with thrombocytopenia syndrome virus entry and interacts with viral gc protein
S Du, Y Wang, J Wang, Y Ma, W Xu… - Journal of Medical …, 2024 - Wiley Online Library
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick‐borne
hemorrhagic fever disease with high fatality rate of 10%–20%. Vaccines or specific …
hemorrhagic fever disease with high fatality rate of 10%–20%. Vaccines or specific …
Sangbaipi decoction exerted in vitro and in vivo anti-influenza effect through inhibiting viral proteins
T Shi, J Lin, S Liang, Y Song, X Zhao, M Xiao… - Journal of …, 2024 - Elsevier
Abstract Headings ethnopharmacological relevance Sangbaipi Decoction (SBPD) is an
effective treatment for lung diseases caused by phlegm-heat obstruction according to …
effective treatment for lung diseases caused by phlegm-heat obstruction according to …
Cyclosporines Antagonize the Antiviral Activity of IFITMProteins by Redistributing Them toward the Golgi Apparatus
Interferon-induced transmembrane proteins (IFITMs) block the fusion of diverse enveloped
viruses, likely through increasing the cell membrane's rigidity. Previous studies have …
viruses, likely through increasing the cell membrane's rigidity. Previous studies have …
IFITM3 restricts porcine deltacoronavirus infection by targeting its Spike protein
J Wu, R Tang, X Zhang, M Gao, L Guo, L Zhang… - Veterinary …, 2024 - Elsevier
The discovery of antiviral molecules is crucial for controlling porcine deltacoronavirus
(PDCoV). Previous studies have provided evidence that the IFN-inducible transmembrane …
(PDCoV). Previous studies have provided evidence that the IFN-inducible transmembrane …
Influenza Virus Host Restriction Factors: The ISGs and Non-ISGs
M Husain - Pathogens, 2024 - mdpi.com
Influenza virus has been one of the most prevalent and researched viruses globally.
Consequently, there is ample information available about influenza virus lifecycle and …
Consequently, there is ample information available about influenza virus lifecycle and …