Programmed and self-organized flow of information during morphogenesis

C Collinet, T Lecuit - Nature Reviews Molecular Cell Biology, 2021 - nature.com
How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

The actin cortex at a glance

P Chugh, EK Paluch - Journal of cell science, 2018 - journals.biologists.com
Precisely controlled cell deformations are key to cell migration, division and tissue
morphogenesis, and have been implicated in cell differentiation during development, as well …

Forcing cells into shape: the mechanics of actomyosin contractility

M Murrell, PW Oakes, M Lenz, ML Gardel - Nature reviews Molecular …, 2015 - nature.com
Actomyosin-mediated contractility is a highly conserved mechanism for generating
mechanical stress in animal cells and underlies muscle contraction, cell migration, cell …

Mechanochemical feedback loops in development and disease

E Hannezo, CP Heisenberg - Cell, 2019 - cell.com
There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

Nonequilibrium physics in biology

X Fang, K Kruse, T Lu, J Wang - Reviews of Modern Physics, 2019 - APS
Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

Mechanochemical principles of spatial and temporal patterns in cells and tissues

A Bailles, EW Gehrels, T Lecuit - Annual review of cell and …, 2022 - annualreviews.org
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

The matrix environmental and cell mechanical properties regulate cell migration and contribute to the invasive phenotype of cancer cells

CT Mierke - Reports on Progress in Physics, 2019 - iopscience.iop.org
The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

Hydrodynamic theory of active matter

F Jülicher, SW Grill, G Salbreux - Reports on Progress in Physics, 2018 - iopscience.iop.org
We review the general hydrodynamic theory of active soft materials that is motivated in
particular by biological matter. We present basic concepts of irreversible thermodynamics of …

[HTML][HTML] Actin flows mediate a universal coupling between cell speed and cell persistence

P Maiuri, JF Rupprecht, S Wieser, V Ruprecht… - Cell, 2015 - cell.com
Cell movement has essential functions in development, immunity, and cancer. Various cell
migration patterns have been reported, but no general rule has emerged so far. Here, we …

Actin cortex mechanics and cellular morphogenesis

G Salbreux, G Charras, E Paluch - Trends in cell biology, 2012 - cell.com
The cortex is a thin, crosslinked actin network lying immediately beneath the plasma
membrane of animal cells. Myosin motors exert contractile forces in the meshwork. Because …