Synaptic adhesion molecules
Formation, differentiation and plasticity of synapses, the specialized cell–cell contacts
through which neurons communicate, all require interactions between pre-and post-synaptic …
through which neurons communicate, all require interactions between pre-and post-synaptic …
Identification of common genetic risk variants for autism spectrum disorder
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …
Genetic evidence suggests posttraumatic stress disorder as a subtype of major depressive disorder
BACKGROUND Major depressive disorder (MDD) and posttraumatic stress disorder (PTSD)
are highly comorbid and exhibit strong correlations with one another. We aimed to …
are highly comorbid and exhibit strong correlations with one another. We aimed to …
Neural immunoglobulin superfamily interaction networks
K Zinn, E Özkan - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Mammalian IgSF subfamilies define small interaction networks.•A global
Drosophila IgSF interaction map identifies complex binding networks.•Large networks with …
Drosophila IgSF interaction map identifies complex binding networks.•Large networks with …
Negr1 controls adult hippocampal neurogenesis and affective behaviors
Recent genome-wide association studies on major depressive disorder have implicated
neuronal growth regulator 1 (Negr1), a GPI-anchored cell adhesion molecule in the …
neuronal growth regulator 1 (Negr1), a GPI-anchored cell adhesion molecule in the …
IgLON cell adhesion molecules are shed from the cell surface of cortical neurons to promote neuronal growth
R Sanz, GB Ferraro, AE Fournier - Journal of Biological Chemistry, 2015 - ASBMB
Matrix metalloproteinases and a disintegrin and metalloproteinases are members of the zinc
endopeptidases, which cleave components of the extracellular matrix as well as cell surface …
endopeptidases, which cleave components of the extracellular matrix as well as cell surface …
Proteomic analysis of synaptosomes using isotope‐coded affinity tags and mass spectrometry
SP Schrimpf, V Meskenaite, E Brunner… - …, 2005 - Wiley Online Library
Synaptosomes are isolated synapses produced by subcellular fractionation of brain tissue.
They contain the complete presynaptic terminal, including mitochondria and synaptic …
They contain the complete presynaptic terminal, including mitochondria and synaptic …
IgLON cell adhesion molecules regulate synaptogenesis in hippocampal neurons
T Hashimoto, S Maekawa… - Cell Biochemistry and …, 2009 - Wiley Online Library
IgLON cell adhesion molecules (CAMs) belonging to the immunoglobulin superfamily
comprise of LAMP, neurotrimin (Ntm), OBCAM, and Kilon. In the present study, we …
comprise of LAMP, neurotrimin (Ntm), OBCAM, and Kilon. In the present study, we …
Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders
Abstract Neuronal growth regulator 1 (NEGR1) belongs to the immunoglobulin (IgLON)
superfamily of cell adhesion molecules involved in cortical layering. Recent functional and …
superfamily of cell adhesion molecules involved in cortical layering. Recent functional and …
Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype
AWS Lee, H Hengstler, K Schwald, M Berriel-Diaz… - 2012 - journals.plos.org
To date, genome-wide association studies (GWAS) have identified at least 32 novel loci for
obesity and body mass-related traits. However, the causal genetic variant and molecular …
obesity and body mass-related traits. However, the causal genetic variant and molecular …