Traumatic spinal cord injury—repair and regeneration

CS Ahuja, S Nori, L Tetreault, J Wilson, B Kwon… - …, 2017 - journals.lww.com
BACKGROUND: Traumatic spinal cord injuries (SCI) have devastating consequences for the
physical, financial, and psychosocial well-being of patients and their caregivers. Expediently …

How mesenchymal stem cells interact with tissue immune responses

Y Shi, J Su, AI Roberts, P Shou, AB Rabson… - Trends in immunology, 2012 - cell.com
Mesenchymal stem cells (MSCs), also called multipotent mesenchymal stromal cells, exist in
almost all tissues and are a key cell source for tissue repair and regeneration. Under …

Mechanisms of mesenchymal stromal cell immunomodulation

K English - Immunology and cell biology, 2013 - Wiley Online Library
Multipotent mesenchymal stromal cells (MSCs) have generated considerable interest in the
fields of regenerative medicine, cell therapy and immune modulation. Over the past 5 years …

Mesenchymal stem cell effects on T-cell effector pathways

MM Duffy, T Ritter, R Ceredig, MD Griffin - Stem cell research & therapy, 2011 - Springer
Mesenchymal stem (stromal) cells (MSCs) are rare, multipotent progenitor cells that can be
isolated and expanded from bone marrow and other tissues. Strikingly, MSCs modulate the …

Concise review: bridging the gap: novel neuroregenerative and neuroprotective strategies in spinal cord injury

CS Ahuja, M Fehlings - Stem cells translational medicine, 2016 - academic.oup.com
Spinal cord injuries (SCIs) result in devastating lifelong disability for patients and their
families. The initial mechanical trauma is followed by a damaging secondary injury cascade …

The immunomodulatory function of mesenchymal stem cells: mode of action and pathways

A Uccelli, NK de Rosbo - Annals of the New York Academy of …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) are being increasingly investigated as a therapeutic
alternative, not only for their possible regenerative potential but also for their …

Immunomodulatory properties and therapeutic application of mesenchymal stem cells

M Shi, ZW Liu, FS Wang - Clinical & Experimental Immunology, 2011 - academic.oup.com
Mesenchymal stem cells (MSCs) are multi-potent progenitor cells that are isolated from the
bone marrow and several adult organs and tissues. These cells possess remarkable …

[HTML][HTML] Recent advances in managing a spinal cord injury secondary to trauma

CS Ahuja, AR Martin, M Fehlings - F1000Research, 2016 - ncbi.nlm.nih.gov
Traumatic spinal cord injuries (SCIs) affect 1.3 million North Americans, producing
devastating physical, social, and vocational impairment. Pathophysiologically, the initial …

Amniotic membrane mesenchymal cells-derived factors skew T cell polarization toward Treg and downregulate Th1 and Th17 cells subsets

S Pianta, P Bonassi Signoroni, I Muradore… - Stem Cell Reviews and …, 2015 - Springer
We previously demonstrated that cells derived from the mesenchymal layer of the human
amniotic membrane (hAMSC) and their conditioned medium (CM-hAMSC) modulate …

Implications of mesenchymal stem cells in regenerative medicine

S Kariminekoo, A Movassaghpour… - Artificial cells …, 2016 - Taylor & Francis
Mesenchymal stem cells (MSCs) are a population of multipotent progenitors which reside in
bone marrow, fat, and some other tissues and can be isolated from various adult and fetal …