Among the major neurodegenerative disorders (NDDs), Alzheimer's disease (AD) and
Parkinson's disease (PD), are a huge socioeconomic burden. Over many centuries, people …

Stroke and myocardial infarction are among the most common causes of mortality and
disability in the world. The ischemic injury underlying these illnesses is complex, involving …

Brain ischemia and reperfusion (I/R) is one of the most severe clinical manifestations of
ischemic stroke, placing a significant burden on both individuals and society. The only FDA …

Background Oxidation, inflammation, and apoptosis are three critical factors for the
pathogenic mechanism of cerebral ischemia/reperfusion (I/R) injury. Curcumin exhibits …

Stroke, as a kind of acute cerebrovascular diseases, has greatly influenced the patients'
quality of life and left a huge public health burden. Vitexin is a flavone C-glycoside (apigenin …

Traditional natural product discovery affords no information about compound structure or
pharmacological activities until late in the discovery process and leads to low probabilities of …

Isorhamnetin, which is a flavonoid predominantly found in fruits and leaves of various plants,
including Hippophae rhamnoides L. and Oenanthe javanica (Blume) DC, is known to …

Paradols are non-pungent and biotransformed metabolites of shogaols and reduce
inflammatory responses as well as oxidative stress as shogaols. Recently, shogaol has …

Ischemic stroke, mostly caused by thromboembolic or thrombotic arterial occlusions, is a
primary leading cause of death worldwide with high morbidity and disability. Unfortunately …

Abstract Ethnopharmacological relevance Pueraria lobata (Willd.) Ohwi is a traditional
medicinal and edible homologous plant rich in flavonoids, triterpenes, saponins …