Does naloxone provision lead to increased substance use? A systematic review to assess if there is evidence of a 'moral hazard'associated with naloxone supply

WC Tse, F Djordjevic, V Borja, L Picco, T Lam… - International Journal of …, 2022 - Elsevier
Background Take home naloxone (THN) programs have been rapidly upscaled in response
to increasing opioid-related mortality. One often cited concern is that naloxone provision …

Amphetamines modulate fentanyl-depressed respiration in a bidirectional manner

HJ Elder, NB Varshneya, DM Walentiny… - Drug and alcohol …, 2023 - Elsevier
Background The opioid epidemic remains one of the most pressing public health crises
facing the United States. Fentanyl and related synthetic opioid agonists have largely driven …

Preliminary effectiveness of online opioid overdose and naloxone administration training and impact of naloxone possession on opioid use

ML Sisson, A Azuero, KR Chichester… - Drug and alcohol …, 2023 - Elsevier
Background Despite the demonstrated value of opioid overdose education and naloxone
distribution (OEND) programs, uptake and utilization remains low. Accessibility to OEND is …

[HTML][HTML] A qualitative examination of naloxone access in three states: Connecticut, Kentucky, and Wisconsin

AL Spector, CL Galletly, EA Christenson… - BMC Public Health, 2022 - Springer
Background Prevention of opioid-involved overdose deaths remains a public health priority
in the United States. While expanding access to naloxone is a national public health …

Digital biomarker applications across the spectrum of opioid use disorder

M Rigatti, B Chapman, PR Chai, D Smelson… - Cogent Mental …, 2023 - Taylor & Francis
Opioid use disorder (OUD) is one of the most pressing public health problems of the past
decade, with over eighty thousand overdose-related deaths in 2021 alone. Digital …

[HTML][HTML] Increasingly powerful opioid antagonists are not necessary

LG Hill, CM Zagorski, LJ Loera - The International Journal on Drug …, 2022 - ncbi.nlm.nih.gov
Background In the United States (US), drug overdose deaths have increased substantially
during the COVID-19 pandemic (Centers for Disease Control and Prevention, 2020) …

[HTML][HTML] “I'm not going to lay back and watch somebody die”: a qualitative study of how people who use drugs' naloxone experiences are shaped by rural risk …

Z Kesich, U Ibragimov, K Komro, K Lane… - Harm Reduction …, 2023 - Springer
Background Overdoses have surged in rural areas in the US and globally for years, but
harm reduction interventions have lagged. Overdose education and naloxone distribution …

Naloxone administration among opioid-involved overdose deaths in 38 United States jurisdictions in the State Unintentional Drug Overdose Reporting System, 2019

K Quinn, S Kumar, CT Hunter, J O'Donnell… - Drug and alcohol …, 2022 - Elsevier
Background The majority of drug overdose deaths in the United States involve opioids, and
synthetic opioid-involved overdose death rates are increasing. Naloxone is a key prevention …

The impact of a peer-navigator program on naloxone distribution and buprenorphine utilization in the emergency department

C Ramdin, M Guo, S Fabricant, C Santos… - Substance Use & …, 2022 - Taylor & Francis
Objectives: In recent years many emergency departments (EDs) have adopted interventions
to help patients with opioid use disorder (OUD), particularly buprenorphine initiation and ED …

[HTML][HTML] Take-Home Naloxone and risk management from the perspective of people who survived an opioid overdose in Stockholm—An analysis informed by drug …

E Holmén, A Hammarberg, M Kåberg… - International Journal of …, 2023 - Elsevier
Abstract Background Take-Home Naloxone (THN) programs were introduced in Sweden in
2018—a country with one of the highest rates of overdose mortality in the EU and a severe …