[HTML][HTML] Mitochondrial dysfunction and therapeutic perspectives in cardiovascular diseases

Y Liu, Y Huang, C Xu, P An, Y Luo, L Jiao… - International Journal of …, 2022 - mdpi.com
High mortality rates due to cardiovascular diseases (CVDs) have attracted worldwide
attention. It has been reported that mitochondrial dysfunction is one of the most important …

Subcellular visualization: Organelle-specific targeted drug delivery and discovery

X Shao, C Meng, W Song, T Zhang, Q Chen - Advanced Drug Delivery …, 2023 - Elsevier
Organelles perform critical biological functions due to their distinct molecular composition
and internal environment. Disorders in organelles or their interacting networks have been …

Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management

M Berk, O Köhler‐Forsberg, M Turner… - World …, 2023 - Wiley Online Library
Populations with common physical diseases–such as cardiovascular diseases, cancer and
neurodegenerative disorders–experience substantially higher rates of major depressive …

[HTML][HTML] On the chemical and biological characteristics of multifunctional compounds for the treatment of Parkinson's Disease

O García-Beltrán, PJ Urrutia, MT Núñez - Antioxidants, 2023 - mdpi.com
Protein aggregation, mitochondrial dysfunction, iron dyshomeostasis, increased oxidative
damage and inflammation are pathognomonic features of Parkinson's disease (PD) and …

[HTML][HTML] Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer

C Rocca, T Soda, EM De Francesco, M Fiorillo… - Journal of Translational …, 2023 - Springer
A large body of evidence indicates the existence of a complex pathophysiological
relationship between cardiovascular diseases and cancer. Mitochondria are crucial …

[HTML][HTML] Mitochondrial transplantation as a novel therapeutic strategy for cardiovascular diseases

M Sun, W Jiang, N Mu, Z Zhang, L Yu, H Ma - Journal of Translational …, 2023 - Springer
Cardiovascular disease (CVD) is the leading cause of noncommunicable disease-related
death worldwide, and effective therapeutic strategies against CVD are urgently needed …

Mitochondrial biomarkers for airborne particulate matter associated cardiovascular diseases

PK Mishra, P Kaur - Current Opinion in Environmental Science & Health, 2023 - Elsevier
Airborne particulate matter pollution has become a significant global health concern due to
its detrimental effects on human health, including cardiovascular diseases (CVDs) …

Associations between mitochondrial copy number, exercise capacity, physiologic cost of walking, and cardiac strain in young adult survivors of childhood cancer

AM Berkman, CG Goodenough, P Durakiewicz… - Journal of Cancer …, 2024 - Springer
Purpose Childhood cancer survivors are at risk for cardiac dysfunction and impaired
physical performance, though underlying cellular mechanisms are not well studied. In this …

Cardioprotective potential of compound 3K, a selective PKM2 inhibitor in isoproterenol-induced acute myocardial infarction: A mechanistic study

M Rihan, SS Sharma - Toxicology and Applied Pharmacology, 2024 - Elsevier
Myocardial infarction (MI) or heart attack arises from acute or chronic prolonged ischemic
conditions in the myocardium. Although several risk factors are associated with MI …

[HTML][HTML] Characterizing early cardiac metabolic programming via 30% maternal nutrient reduction during fetal development in a non-human primate model

SP Pereira, MS Diniz, LC Tavares… - International Journal of …, 2023 - mdpi.com
Intra-uterine growth restriction (IUGR) is a common cause of fetal/neonatal morbidity and
mortality and is associated with increased offspring predisposition for cardiovascular …