Aptamers are nucleic acid-based scaffolds that can bind with high affinity to a variety of
biological targets. Aptamers are identified from large DNA or RNA libraries through a …

DNA polymerases play a central role in biology by transferring genetic information from one
generation to the next during cell division. Harnessing the power of these enzymes in the …

Natural DNA is exquisitely evolved to store genetic information. The chirally inverted l-DNA,
possessing the same informational capacity but resistant to biodegradation, may serve as a …

Conspectus Nucleic acids are a distinct form of sequence-defined biopolymer. What sets
them apart from other biopolymers such as polypeptides or polysaccharides is their unique …

Polymerases evolved in nature to synthesize DNA and RNA, and they underlie the storage
and flow of genetic information in all cells. The availability of these enzymes for use at the …

The development of SELEX (Selective Enhancement of Ligands by Exponential Enrichment)
provides a powerful tool for the search of functional oligonucleotides with the ability to bind …

DNA polymerases are essential enzymes that play a key role in living organisms, as they
participate in the synthesis and maintenance of the DNA molecule. The intrinsic properties of …

Phosphazene chemistry continues to expand in its breadth and application. This article
discusses new research published in 2013 covering mono-and dimeric structures …

Pfu DNA polymerase is one of the most preferred molecular enzymes that is isolated from
the hyperthermophilic Pyrococcus furiosus and used for high-throughput DNA synthesis by …

An efficient induction strategy that consisted of multiple additions of small doses of isopropyl-
β-D-thiogalactopyranoside (IPTG) in the early cell growth phase was developed for …