HIV genetic diversity and drug resistance

AF Santos, MA Soares - Viruses, 2010 - mdpi.com
Most of the current knowledge on antiretroviral (ARV) drug development and resistance is
based on the study of subtype B of HIV-1, which only accounts for 10% of the worldwide HIV …

[HTML][HTML] The increasing prevalence of HIV-1 subtype C in Southern Brazil and its dispersion through the continent

T Gräf, AR Pinto - Virology, 2013 - Elsevier
The HIV-1 has evolved swiftly and the scenario of HIV-1 genetic diversity is constantly
changing. In South America, recombinant forms of subtypes B, F1, and BF1 have historically …

Origin and evolutionary history of HIV-1 subtype C in Brazil

G Bello, CPB Passaes, ML Guimaraes, RS Lorete… - Aids, 2008 - journals.lww.com
Objective: To investigate the origin and to reconstruct the onset date of the HIV-1 subtype C
epidemic in Brazil. Design: Three independent datasets of subtype C sequences isolated …

The HIV-1 subtype C epidemic in South America is linked to the United Kingdom

T de Oliveira, D Pillay, RJ Gifford… - PloS one, 2010 - journals.plos.org
Background The global spread of HIV-1 has been accompanied by the emergence of
genetically distinct viral strains. Over the past two decades subtype C viruses, which …

Increase of non-B subtypes and recombinants among newly diagnosed HIV-1 native Spaniards and immigrants in Spain

A Holguín, M Mulder, G Yebra, M López… - Current HIV …, 2008 - ingentaconnect.com
Although HIV-1 clade B variants are predominant in Western Europe, non-B subtypes are
rapidly spreading, mainly due to immigration from endemic regions. All newly diagnosed …

Estimating HIV-1 genetic diversity in Brazil through next-generation sequencing

BM Alves, JD Siqueira, IM Prellwitz… - Frontiers in …, 2019 - frontiersin.org
Approximately 36.7 million people were living with the human immunodeficiency virus (HIV)
at the end of 2016 according to UNAIDS, representing a global prevalence rate of 0.8%. In …

Moderate prevalence of transmitted drug resistance and high HIV‐1 genetic diversity in patients from Mato Grosso State, Central Western Brazil

AS Ferreira, LPV Cardoso… - Journal of medical …, 2011 - Wiley Online Library
Few reports have described the molecular characteristics of the AIDS epidemic within the
interior regions of Brazil, a country of continental dimensions. To help fill this gap, the …

High-resolution phylogenetics and phylogeography of human immunodeficiency virus type 1 subtype C epidemic in South America

NMC Véras, RR Gray… - Journal of general …, 2011 - microbiologyresearch.org
Human immunodeficiency virus type 1 subtype C (HIV-1C) represents 30–65% of HIV
infections in southern Brazil, and isolated cases of HIV-1C infection have also been reported …

Characterization of HIV-1 near full-length proviral genome quasispecies from patients with undetectable viral load undergoing first-line HAART therapy

BM Alves, JD Siqueira, MM Garrido, OM Botelho… - Viruses, 2017 - mdpi.com
Increased access to highly active antiretroviral therapy (HAART) by human
immunodeficiency virus postive (HIV+) individuals has become a reality worldwide. In Brazil …

Phylogeographic analysis of HIV-1 subtype C dissemination in Southern Brazil

G Bello, PMA Zanotto, A Iamarino, T Gräf, AR Pinto… - PLoS …, 2012 - journals.plos.org
The HIV-1 subtype C has spread efficiently in the southern states of Brazil (Rio Grande do
Sul, Santa Catarina and Paraná). Phylogeographic studies indicate that the subtype C …