Since its debut in the biomedical research fields in 1981, zebrafish have been used as a
vertebrate model organism in more than 40,000 biomedical research studies. Especially …

Highlights•Zebrafish are a useful tool for screening new drugs for inflammation.•This teleost
shares several inflammatory mediators and receptors with mammals.•The real-time …

We report the evolution of mScarlet3, a cysteine-free monomeric red fluorescent protein with
fast and complete maturation, as well as record brightness, quantum yield (75%) and …

Conditional targeted cell ablation in zebrafish would greatly expand the utility of this genetic
model system in developmental and regeneration studies, given its extensive regenerative …

Ablation studies are used to elucidate cell lineage relationships, developmental roles for
specific cells during embryogenesis and mechanisms of tissue regeneration. Previous …

In order to generate a zebrafish model of β cell regeneration, we have expressed an
Escherichia coli gene called nfsB in the β cells of embryonic zebrafish. This bacterial gene …

Amongst animal species, there is enormous variation in the size and complexity of the heart,
ranging from the simple one-chambered heart of Ciona intestinalis to the complex four …

Zebrafish are making big waves in the field of cancer research. The effect has been
widespread and continues to gain speed as more and more cancer researchers ride the …

The swimbladder is a hydrostatic organ in fish postulated as a homolog of the tetrapod lung.
While lung development has been well studied, the molecular mechanism of swimbladder …

Background Early events in vertebrate liver development have been the major focus in
previous studies, however, late events of liver organogenesis remain poorly understood …