Microtubules as a potential platform for energy transfer in biological systems: a target for implementing individualized, dynamic variability patterns to improve organ …

Y Ilan - Molecular and Cellular Biochemistry, 2023 - Springer
Variability characterizes the complexity of biological systems and is essential for their
function. Microtubules (MTs) play a role in structural integrity, cell motility, material transport …

Baicalein attenuates inflammatory responses by suppressing TLR4 mediated NF-κB and MAPK signaling pathways in LPS-induced mastitis in mice

X He, Z Wei, E Zhou, L Chen, J Kou, J Wang… - International …, 2015 - Elsevier
Baicalein is a phenolic flavonoid presented in the dry roots of Scutellaria baicalensis Georgi.
It has been reported that baicalein possesses a number of biological properties, such as …

Mechanotransduction pathways in articular chondrocytes and the emerging role of estrogen receptor-α

N Wang, Y Lu, BB Rothrauff, A Zheng, A Lamb, Y Yan… - Bone Research, 2023 - nature.com
In the synovial joint, mechanical force creates an important signal that influences
chondrocyte behavior. The conversion of mechanical signals into biochemical cues relies on …

Linalool inhibits cigarette smoke-induced lung inflammation by inhibiting NF-κB activation

J Ma, H Xu, J Wu, C Qu, F Sun, S Xu - International immunopharmacology, 2015 - Elsevier
Linalool, a natural compound that exists in the essential oils of several aromatic plants
species, has been reported to have anti-inflammatory effects. However, the effects of linalool …

Linalool inhibits LPS-induced inflammation in BV2 microglia cells by activating Nrf2

Y Li, O Lv, F Zhou, Q Li, Z Wu, Y Zheng - Neurochemical research, 2015 - Springer
Linalool, a natural compound of the essential oils, has been reported to have anti-
inflammatory effects. This study aimed to investigate the anti-inflammatory effects and …

[HTML][HTML] Cdc42 and its BORG2 and BORG3 effectors control the subcellular localization of septins between actin stress fibers and microtubules

J Salameh, I Cantaloube, B Benoit, C Poüs, A Baillet - Current Biology, 2021 - cell.com
Cell resistance to taxanes involves several complementary mechanisms, among which
septin relocalization from actin stress fibers to microtubules plays an early role. By …

Interphase microtubules in nuclear organization and genome maintenance

M Shokrollahi, K Mekhail - Trends in cell biology, 2021 - cell.com
Microtubules are major cytoskeletal components mediating fundamental cellular processes,
including cell division. Recent evidence suggests that microtubules also regulate the …

Osteoblast lineage cells play an essential role in periodontal bone loss through activation of nuclear factor-kappa B

S Pacios, W Xiao, M Mattos, J Lim, RS Tarapore… - Scientific reports, 2015 - nature.com
Bacterial pathogens stimulate periodontitis, the most common osteolytic disease in humans
and the most common cause of tooth loss in adults. Previous studies identified leukocytes …

Angelicin—A Furocoumarin compound with vast biological potential

CK Mahendra, LTH Tan, WL Lee, WH Yap… - Frontiers in …, 2020 - frontiersin.org
Angelicin, a member of the furocoumarin group, is related to psoralen which is well known
for its effectiveness in phototherapy. The furocoumarins as a group have been studied since …

Chemotherapy-induced peripheral neuropathy and changes in cytoskeleton

A Malacrida, C Meregalli… - International journal of …, 2019 - mdpi.com
Despite the different antineoplastic mechanisms of action, peripheral neurotoxicity induced
by all chemotherapy drugs (anti-tubulin agents, platinum compounds, proteasome inhibitors …