Biomimetic and bioinspired nano‐platforms for cancer vaccine development

C Feng, P Tan, G Nie, M Zhu - Exploration, 2023 - Wiley Online Library
The advent of immunotherapy has revolutionized the treating modalities of cancer. Cancer
vaccine, aiming to harness the host immune system to induce a tumor‐specific killing effect …

Nanotechnology-empowered vaccine delivery for enhancing CD8+ T cells-mediated cellular immunity

G Liu, M Zhu, X Zhao, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
After centuries of development, using vaccination to stimulate immunity has become an
effective method for prevention and treatment of a variety of diseases including infective …

Nanocomplex‐mediated in vivo programming to chimeric antigen receptor‐M1 macrophages for cancer therapy

M Kang, SH Lee, M Kwon, J Byun, D Kim… - Advanced …, 2021 - Wiley Online Library
Chimeric antigen receptor‐T (CAR‐T) cell immunotherapy has shown impressive clinical
outcomes for hematologic malignancies. However, its broader applications are challenged …

Liposome-based delivery of biological drugs

KT Magar, GF Boafo, X Li, Z Chen, W He - Chinese Chemical Letters, 2022 - Elsevier
Biological drugs are attracting tremendous attention in disease treatment. However, their
application is significantly limited by their inherent properties, such as high hydrophilicity …

Enhanced antitumor immunity by targeting dendritic cells with tumor cell lysate-loaded chitosan nanoparticles vaccine

GN Shi, CN Zhang, R Xu, JF Niu, HJ Song, XY Zhang… - Biomaterials, 2017 - Elsevier
Whole tumor cell lysates (TCL) have been implemented as tumor antigens for cancer
vaccine development, although clinical outcomes of TCL-based antitumor immunotherapy …

Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells

D Sarhan, F Cichocki, B Zhang, A Yingst, SR Spellman… - Cancer research, 2016 - AACR
Human cytomegalovirus (CMV)-induced adaptive natural killer (NK) cells display distinct
phenotypic and functional characteristics, including properties of immune memory. We …

Nanotechnology platforms for cancer immunotherapy

Z Yang, Y Ma, H Zhao, Y Yuan… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Various cancer therapies have advanced remarkably over the past decade. Unlike the direct
therapeutic targeting of tumor cells, cancer immunotherapy is a new strategy that boosts the …

Engineered nanodelivery systems to improve DNA vaccine technologies

M Lim, AZM Badruddoza, J Firdous, M Azad, A Mannan… - Pharmaceutics, 2020 - mdpi.com
DNA vaccines offer a flexible and versatile platform to treat innumerable diseases due to the
ease of manipulating vaccine targets simply by altering the gene sequences encoded in the …

Multifunctional nanoparticles for cancer immunotherapy: A groundbreaking approach for reprogramming malfunctioned tumor environment

S Sau, HO Alsaab, K Bhise, R Alzhrani, G Nabil… - Journal of Controlled …, 2018 - Elsevier
Several cancer immunotherapy approaches have been recently introduced into the clinics
and they have shown remarkable therapeutic potentials. The groundbreaking cancer …

Nanoparticle systems for cancer vaccine

R Wen, AC Umeano, Y Kou, J Xu, AA Farooqi - Nanomedicine, 2019 - Taylor & Francis
As effective tools for public health, vaccines prevent disease by priming the body's adaptive
and innate immune responses against an infection. Due to advances in understanding …