MicroRNAs in kidney injury and disease

N Mahtal, O Lenoir, C Tinel, D Anglicheau… - Nature Reviews …, 2022 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

Current insights on biomarkers in lupus nephritis: a systematic review of the literature

L Palazzo, J Lindblom, C Mohan, I Parodis - Journal of Clinical Medicine, 2022 - mdpi.com
Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

Three-step one-way model in terahertz biomedical detection

Y Peng, J Huang, J Luo, Z Yang, L Wang, X Wu… - PhotoniX, 2021 - Springer
Terahertz technology has broad application prospects in biomedical detection. However, the
mixed characteristics of actual samples make the terahertz spectrum complex and difficult to …

Emerging molecular markers towards potential diagnostic panels for lupus

G Tan, B Baby, Y Zhou, T Wu - Frontiers in Immunology, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease which can affect
various tissues and organs, posing significant challenges for clinical diagnosis and …

Challenges and promise of targeting miRNA in rheumatic diseases: A computational approach to identify miRNA association with cell types, cytokines, and disease …

FS Shaikh, RJ Siegel, A Srivastava, DA Fox… - Frontiers in …, 2024 - frontiersin.org
MicroRNAs (miRNAs) are small non-coding RNAs that alter the expression of target genes
at the post-transcriptional level, influencing diverse outcomes in metabolism, cell …

MicroRNAs in lupus nephritis–role in disease pathogenesis and clinical applications

BYF So, DYH Yap, TM Chan - International journal of molecular sciences, 2021 - mdpi.com
MicroRNAs (miRs) are non-coding small RNAs that act as epigenetic modulators to regulate
the protein levels of target mRNAs without modifying the genetic sequences. The role of …

Lupus nephritis biomarkers: a critical review

FK Alduraibi, GC Tsokos - International Journal of Molecular Sciences, 2024 - mdpi.com
Lupus nephritis (LN), a major complication in individuals diagnosed with systemic lupus
erythematosus, substantially increases morbidity and mortality. Despite marked …

Identification and contribution of inflammation-induced novel MicroRNA in the pathogenesis of systemic lupus erythematosus

RP Singh, BH Hahn, DS Bischoff - Frontiers in Immunology, 2022 - frontiersin.org
Recently microRNAs (miRNAs) have been recognized as powerful regulators of many
genes and pathways involved in the pathogenesis of inflammatory diseases including …

Genomics of human fibrotic diseases: disordered wound healing response

RC Stone, V Chen, J Burgess, S Pannu… - International journal of …, 2020 - mdpi.com
Fibrotic disease, which is implicated in almost half of all deaths worldwide, is the result of an
uncontrolled wound healing response to injury in which tissue is replaced by deposition of …

Circulatory microRNAs and proinflammatory cytokines as predictors of lupus nephritis

DS ElFeky, NM Omar, OG Shaker… - Frontiers in …, 2024 - frontiersin.org
Introduction Lupus nephritis (LN) is one of the most prevalent severe organ manifestations of
systemic lupus erythematosus (SLE), impacting 70% of SLE patients. MicroRNAs (miRNAs) …