Simple Summary Germline genetic testing for patients with cancer can have important
implications for treatment, preventive options, and for family members. In a mainstream …

BRCA1 and BRCA2 are tumor suppressor genes that have been linked to inherited
susceptibility of breast cancer. Germline BRCA1/2 pathogenic or likely pathogenic variants …

In the 20 years since the initial sequencing of the human genome, genomics has become
increasingly relevant to nursing. We sought to chart the current state of genomics in nursing …

Lynch syndrome (LS) is an autosomal dominant condition that increases an individual's risk
of a constellation of cancers. LS is defined when an individual has inherited pathogenic …

Background In international guidelines, germline genetic testing is recommended for
patients with metastatic prostate cancer. Before undergoing germline genetic testing, these …

Genetic and genomic data are increasingly guiding clinical care for cancer patients. To meet
the growing demand for precision medicine, patient-facing oncology staff will be a part of …

The United Kingdom is recognised worldwide as a leader in genomics. The use of genomic
technologies in the National Health Service (NHS) is expected to deliver faster and more …

With the advent of poly‐ADP‐ribose polymerase inhibitor (PARPi) therapies, the focus of
genetic testing for breast, ovarian, and other cancers has shifted from risk management to …

Background Pre-test genetic counseling of patients with breast cancer is increasingly being
offered by non-genetic healthcare professionals. We aimed to evaluate the experiences of …

Background This paper explores and discusses local challenges oncologists face for
diagnosing and managing breast cancer patients with BRCA gene mutations in Jordan …