Matrix metalloproteinases as biomarkers of atherosclerotic plaque instability

W Olejarz, D Łacheta… - International journal of …, 2020 - mdpi.com
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases
responsible for tissue remodeling and degradation of extracellular matrix (ECM) proteins …

The role of matrix metalloproteinase‐9 in atherosclerotic plaque instability

T Li, X Li, Y Feng, G Dong, Y Wang… - Mediators of …, 2020 - Wiley Online Library
Matrix metalloproteinase‐9 (MMP‐9) belongs to the MMP family and has been widely
investigated. Excessive MMP‐9 expression can enhance extracellular matrix degradation …

Modulating Plaque Inflammation via Targeted mRNA Nanoparticles for the Treatment of Atherosclerosis

M Gao, M Tang, W Ho, Y Teng, Q Chen, L Bu, X Xu… - ACS …, 2023 - ACS Publications
Atherosclerosis is a common pathology present in many cardiovascular diseases. Although
the current therapies (including statins and inhibitors of the serine protease PCSK9) can …

[HTML][HTML] Atherosclerotic cardiovascular disease risk assessment: An American Society for Preventive Cardiology clinical practice statement

ND Wong, MJ Budoff, K Ferdinand, IM Graham… - American journal of …, 2022 - Elsevier
Risk for atherosclerotic cardiovascular disease (ASCVD) shows considerable heterogeneity
both in generally healthy persons and in those with known ASCVD. The foundation of …

Inflammatory factors driving atherosclerotic plaque progression new insights

B Song, Y Bie, H Feng, B Xie, M Liu… - Journal of Translational …, 2022 - degruyter.com
Coronary atherosclerosis is a chronic inflammatory disease that can lead to varying degrees
of blood flow obstruction and a common pathophysiological basis of cardiovascular disease …

Macrophage profiling in atherosclerosis: understanding the unstable plaque

I Gianopoulos, SS Daskalopoulou - Basic Research in Cardiology, 2024 - Springer
The development and rupture of atherosclerotic plaques is a major contributor to myocardial
infarctions and ischemic strokes. The dynamic evolution of the plaque is largely attributed to …

Lipoprotein (a), immune cells and cardiovascular outcomes in patients with premature coronary heart disease

OI Afanasieva, AV Tyurina, EA Klesareva… - Journal of Personalized …, 2022 - mdpi.com
The detection of lipoprotein (a)[Lp (a)] in the artery wall at the stage of lipid-bands formation
may indicate that it participates in the atherosclerosis local nonspecific inflammatory …

Use of 3D Printing Techniques to Fabricate Implantable Microelectrodes for Electrochemical Detection of Biomarkers in the Early Diagnosis of Cardiovascular and …

N Zilinskaite, RP Shukla… - ACS Measurement Science …, 2023 - ACS Publications
This Review provides a comprehensive overview of 3D printing techniques to fabricate
implantable microelectrodes for the electrochemical detection of biomarkers in the early …

Risk factors for frailty and cardiovascular diseases: are they the same?

K Piotrowicz, J Gąsowski - … and Cardiovascular Diseases: Research into an …, 2020 - Springer
Cardiovascular disease burden increases with the increasing age of populations. Also, with
increasing longevity, some individuals are ageing along an unfavourable path developing …

Cell-derived biomimetic nanoparticles as a novel drug delivery system for atherosclerosis: predecessors and perspectives

L Yang, G Zang, J Li, X Li, Y Li… - Regenerative …, 2020 - academic.oup.com
Atherosclerosis is a key mechanism underlying the pathogenesis of cardiovascular disease,
which is associated with high morbidity and mortality. In the field of precision medicine for …