Non-coding RNA networks in cancer

E Anastasiadou, LS Jacob, FJ Slack - Nature Reviews Cancer, 2018 - nature.com
Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

Exploring miRNA based approaches in cancer diagnostics and therapeutics

S Mishra, T Yadav, V Rani - Critical reviews in oncology/hematology, 2016 - Elsevier
MicroRNAs (miRNAs), a highly conserved class of tissue specific, small non-protein coding
RNAs maintain cell homeostasis by negative gene regulation. Proper controlling of miRNA …

miRNAs driving diagnosis, prognosis and progression in Merkel cell carcinoma

TM Al-Noshokaty, MS Elballal, GK Helal… - … -Research and Practice, 2023 - Elsevier
Merkel cell carcinoma (MCC) is a rare, aggressive form of skin malignancy with a high
recurrence commonly within two to three years of initial diagnosis. The incidence of MCC …

Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients

E Endzeliņš, A Berger, V Melne, C Bajo-Santos… - BMC cancer, 2017 - Springer
Background Circulating cell-free miRNAs have emerged as promising minimally-invasive
biomarkers for early detection, prognosis and monitoring of cancer. They can exist in the …

The MicroRNA family gets wider: the IsomiRs classification and role

L Tomasello, R Distefano, G Nigita… - Frontiers in cell and …, 2021 - frontiersin.org
MicroRNAs (miRNAs or miRs) are the most characterized class of non-coding RNAs and are
engaged in many cellular processes, including cell differentiation, development, and …

MicroRNA dysregulations in Merkel cell carcinoma: Molecular mechanisms and clinical applications

C Mazziotta, CF Cervellera, C Lanzillotti… - Journal of Medical …, 2023 - Wiley Online Library
Merkel cell carcinoma (MCC) is an aggressive skin malignancy with two distinct etiologies.
The first, which accounts for the highest proportion, is caused by Merkel cell polyomavirus …

MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis

J Gan, S Liu, Y Zhang, L He, L Bai, R Liao… - … & molecular medicine, 2022 - nature.com
The functional role of microRNA-375 (miR-375) in the development of prostate cancer (PCa)
remains controversial. Previously, we found that plasma exosomal miR-375 is significantly …

MicroRNAs in prostate cancer: Functional role as biomarkers

R Kanwal, AR Plaga, X Liu, GC Shukla, S Gupta - Cancer Letters, 2017 - Elsevier
MicroRNAs (miRNAs) are small endogenous non-coding molecules that alters gene
expression through post-transcriptional regulation of messenger RNA. Compelling evidence …

Epigenetic dysregulations in merkel cell polyomavirus-driven merkel cell carcinoma

JC Rotondo, C Mazziotta, C Lanzillotti… - International Journal of …, 2021 - mdpi.com
Merkel cell polyomavirus (MCPyV) is a small DNA virus with oncogenic potential. MCPyV is
the causative agent of Merkel Cell Carcinoma (MCC), a rare but aggressive tumor of the …

Circulating microRNAs as biomarkers for prostate cancer detection and metastasis development prediction

D Bidarra, V Constâncio, D Barros-Silva… - Frontiers in …, 2019 - frontiersin.org
Prostate Cancer (PCa) overdiagnosis and overtreatment, as a consequence of the limited
specificity of current detection and prognostication methods, remains a major challenge in …