This part of ISO 10993 assesses possible contact hazards from chemicals released from
medical devices that may produce skin and mucosal irritation, eye irritation and delayed …

A series of tests was conducted to obtain a profile of the toxicity of epichlorohydrin since this
compound finds a number of industrial applications, including synthesis of some epoxy …

Twelve phthalic acid esters, including those commonly used as plasticizers for biomedical
devices, were subjected to various biological tests for acute, short-term, and chronic toxicity …

A series of systemic toxicity tests for various types of compounds are presented with
illustrative data and discussed in regard to their relevance as potential screening tests for …

Chloroacetaldehyde, a probable metabolite of 2-chloroethanol (ethylene chlorohydrin), was
studied in a number of in vivo animal systems, in in vitro hemolysis tests, and in tissue …

This paper describes the validation of an allograft sterilization method specifically designed
for the processing methods used at AlloSource in Centennial, CO. The methods used for this …

This chapter reviews linear and branched C7 to C18 monohydric aliphatic alcohols, as well
as aromatic, alicyclic, aliphatic unsaturated, and aliphatic halogenated alcohols. The CAS …

It is essential to control bioburden levels on final allograft products in order to ensure that the
aseptic process used to produce the final allograft products is under control and within the …

The effect of 2‐chloroethanol on the activities of hepatic microsomal enzymes in the rat has
been studied. A significant reduction in activities of drug‐metabolizing enzymes …

This chapter reviews linear and branched C7 to C18 monohydric aliphatic alcohols, as well
as aromatic, alicyclic, aliphatic unsaturated, and aliphatic halogenated alcohols. The CAS …