Comparative risk of serious infections with biologic agents and oral small molecules in inflammatory bowel diseases: a systematic review and meta-analysis

V Solitano, A Facciorusso, T Jess, C Ma… - Clinical …, 2023 - Elsevier
Background & Aims Safety is a key consideration when choosing advanced therapies
(biologic agents and oral small-molecule inhibitors/modulators) in patients with inflammatory …

How to choose the biologic therapy in a bio-naïve patient with inflammatory bowel disease

V Laredo, CJ Gargallo-Puyuelo… - Journal of Clinical …, 2022 - mdpi.com
The availability of biologic therapies in inflammatory bowel disease (IBD) is increasing
significantly. This represents more options to treat patients, but also more difficulties in …

Effectiveness and safety of vedolizumab in inflammatory bowel disease: a comprehensive meta-analysis of observational studies

FS Macaluso, M Ventimiglia… - Journal of Crohn's and …, 2023 - academic.oup.com
Abstract Background and Aims Many observational studies on the use of vedolizumab [VDZ]
in patients with Crohn's disease [CD] and ulcerative colitis [UC] have been published in the …

Biologic therapy for inflammatory bowel disease: Real-world comparative effectiveness and impact of drug sequencing in 13 222 patients within the UK IBD …

C Kapizioni, R Desoki, D Lam… - Journal of Crohn's …, 2024 - academic.oup.com
Abstract Background and Aims This study compares the effectiveness of different biologic
therapies and sequences in patients with inflammatory bowel disease [IBD] using real-world …

Meta‐analysis: persistence of advanced therapies in the treatment of inflammatory bowel disease

TH Yiu, Y Ko, A Pudipeddi, P Natale… - Alimentary …, 2024 - Wiley Online Library
Background The expanding options in advanced therapies for ulcerative colitis (UC) and
Crohn's disease (CD) present challenges in treatment selection. Persistence analysis …

Real-life treatment persistence and treatment outcomes of Finnish patients with inflammatory bowel disease receiving vedolizumab as first-line biological treatment

T Ylisaukko-oja, CG af Björkesten, A Eberl, H Nuutinen… - Heliyon, 2024 - cell.com
Purpose To analyze treatment persistence and treatment outcomes of vedolizumab as first-
line biological treatment in Crohn's disease (CD) and ulcerative colitis (UC) patients in a …

Efficacy and safety of adalimumab biosimilar (HS016) in inflammatory bowel disease from the real-world study

F Wang, X Li, Y Shi, H Zhou, G Yang, R Li… - Frontiers in …, 2023 - frontiersin.org
Objective: Adalimumab (ADA) is an effective treatment for inflammatory bowel disease (IBD),
both ulcerative colitis (UC) and Crohn's disease (CD). The equal effect between the original …

Impact of Prior Biologic or Janus Kinase Inhibitor Therapy on Efficacy and Safety of Etrasimod in the ELEVATE UC 52 and ELEVATE UC 12 Trials

S Vermeire, BE Sands, L Peyrin-Biroulet… - Journal of Crohn's …, 2024 - academic.oup.com
Abstract Background and Aims Etrasimod is an oral, once daily, selective sphingosine 1-
phosphate [S1P] 1, 4, 5 receptor modulator for the treatment of moderately to severely active …

Comparative risk of serious infection with vedolizumab vs anti-TNF in inflammatory bowel disease: results from nationwide Swedish registers

S Karlqvist, MC Sachs, C Eriksson, Y Cao… - Official journal of the …, 2022 - journals.lww.com
Objectives: We aimed to assess the risk of serious infection in inflammatory bowel disease
(IBD) patients treated with vedolizumab, compared to those treated with anti-tumor necrosis …

Viszeralmedizin 2022 (DGVS): Real-World-Daten untermauern die Evidenz klinischer Studien und liefern wichtige Erkenntnisse für die Wahl der Therapie bei CED

M Crohn - 2023 - search.proquest.com
Wie wichtig es ist, auch schon bei jungen Patienten frühzeitig mit einer First-line-
Biologikatherapie zu beginnen, demonstrierte Blumenstein anhand eines Patientenfalles …