In recent years, visible light-induced transition metal catalysis has emerged as a new
paradigm in organic photocatalysis, which has led to the discovery of unprecedented …

Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

The development of transition metal (TM) catalysis for organic synthesis under visible light
without recourse to typical photoredox catalysts has become a rapidly growing area of …

The polarity of a radical intermediate profoundly impacts its reactivity and selectivity. To
quantify this influence and predict its effects, the electrophilicity/nucleophilicity of> 500 …

The selective functionalization of remote C–H bonds via intramolecular hydrogen atom
transfer (HAT) is transformative for organic synthesis. This radical-mediated strategy …

Selective functionalization of ubiquitous unactivated C–H bonds is a continuous quest for
synthetic organic chemists. In addition to transition metal catalysis, which typically operates …

Direct synthesis of ketones from aldehydes features high atom-and step-economy. Yet, the
coupling of aldehydes with unactivated alkyl C (sp3)-H remains challenging. Herein, we …

The value of catalytic dehydrogenation of aliphatics (CDA) in organic synthesis has
remained largely underexplored. Known homogeneous CDA systems often require the use …

A visible light-induced palladium-catalyzed homologative three-component synthesis of
allylic amines has been developed. This protocol proceeds via a unique mechanism …

The palladium-catalyzed Mizoroki–Heck reaction is arguably one of the most significant
carbon–carbon bond-construction reactions to be discovered in the last 50 years, with a …