Poly (ethylene glycol) alternatives in biomedical applications

X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …

Polyoxazoline: A review article from polymerization to smart behaviors and biomedical applications

SN Mahand, S Aliakbarzadeh, A Moghaddam… - European Polymer …, 2022 - Elsevier
Abstract Poly (2-oxazoline) s are emerging innovative biomaterials that show analogous and
even preferable properties compared to well-known counterparts, especially poly (ethylene …

The future of poly (2-oxazoline) s

R Hoogenboom - European Polymer Journal, 2022 - Elsevier
Abstract Poly (2-oxazoline) s have gained significant interest in the past decade, especially
driven by their high potential for biomedical applications, amongst others to substitute poly …

Poly (2-oxazoline)–Ferrostatin-1 drug conjugates inhibit ferroptotic cell death

JP Morrow, ZAI Mazrad, AI Bush, K Kempe - Journal of Controlled Release, 2022 - Elsevier
Ferroptosis is a form of non-apoptotic iron induced cell death mechanism implicated in
neurodegeneration, yet can be ameliorated with potent radical scavengers such as …

Non‐activated Esters as Reactive Handles in Direct Post‐Polymerization Modification

JFR Van Guyse, Y Bernhard, A Podevyn… - Angewandte …, 2023 - Wiley Online Library
Non‐activated esters are prominently featured functional groups in polymer science, as
ester functional monomers display great structural diversity and excellent compatibility with a …

Accelerated Post‐Polymerization Amidation of Polymers with Side‐Chain Ester Groups by Intramolecular Activation

JFR Van Guyse, MN Leiske, J Verjans… - Angewandte …, 2022 - Wiley Online Library
The catalytic conversion of esters to amides represents new opportunities in the synthetic
diversification and upcycling of polymers, as esters are commonly featured in various …

Triazabicyclodecene: A versatile catalyst for polymer synthesis

JG Kim, GS Lee, A Lee - Journal of Polymer Science, 2024 - Wiley Online Library
This comprehensive review aims to provide an in‐depth analysis of the catalytic
performance of 1, 5, 7‐triazabicyclo [4, 4, 0] dec‐5‐ene (TBD) in polymer synthesis. TBD, a …

[HTML][HTML] Recent developments in synthetic approaches for macromolecular prodrugs

J Alex, C Weber, C Guerrero-Sanchez… - Progress in Polymer …, 2024 - Elsevier
In the last decades, nanoscale drug delivery systems have gained great attention partly due
to their ability to improve the bioavailability of water insoluble drugs. To this end, the general …

Thermoresponsive polymer–antibiotic conjugates based on gradient copolymers of 2-oxazoline and 2-oxazine

JR Park, AD Verderosa, M Totsika… - …, 2021 - ACS Publications
A polymer–antibiotic conjugate with thermoresponsive properties near body temperature is
presented. The backbone polymer is a copolymer of 2-n-propyl-2-oxazine (PropOzi) and …

Determination of ω-end functionalities in tailored poly(2-alkyl-2-oxazoline)s by liquid chromatography and mass spectrometry

N Engel, M Dirauf, JA Czaplewska… - Royal Society …, 2024 - royalsocietypublishing.org
The in-depth analytical characterization of polymers, in particular regarding intended
biomedical applications, is becoming increasingly important to elucidate their structure …