Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

This review presents a brief overview of the γ-aminobutyric acid (GABA) system in the
developing and mature central nervous system (CNS) and its potential connections to …

Developing networks follow common rules to shift from silent cells to coactive networks that
operate via thousands of synapses. This review deals with some of these rules and in …

Brain function operates through the coordinated activation of neuronal assemblies. Graph
theory predicts that scale-free topologies, which include “hubs”(superconnected nodes), are …

▪ Abstract Many neurons in the mammalian central nervous system communicate through
electrical synapses, defined here as gap junction–mediated connections. Electrical …

Encoding of information in the cortex is thought to depend on synchronous firing of cortical
neurons,. Inhibitory neurons are known to be critical in the coordination of cortical activity …

The generation of pacemaker activity in heart and brain is mediated by hyperpolarization-
activated cation channels that are directly regulated by cyclic nucleotides. We previously …

The main ionotropic receptors (GABA A, NMDA and AMPA) display a sequential
participation in neuronal excitation in the neonatal hippocampus. GABA, the principal …

Coherent oscillations, in which ensembles of neurons fire in a repeated and synchronous
manner, are thought to be important in higher brain functions. In the hippocampus, these …

During development, when synapses start to be established, a primitive form of network-
driven activity provides most of the synaptic activity. This pattern enables a high degree of …