SUMMARY CD8 T cells are crucial adaptive immune cells with cytotoxicity to fight against
pathogens or abnormal self-cells via major histocompatibility complex class I-dependent …

Background T cell dysregulation is a common event in leukemia. Recent findings have
indicated that aberrant expression of immune checkpoint proteins may be associated with …

The presence of CD8+ T cells with a memory phenotype in nonimmunized mice has been
noted for decades, but it was not until about 2 decades ago that they began to be studied in …

Background Aplastic anemia (AA) is known as an autoimmune disease in which T cell
activation is aberrant. It has been reported that unconventional T cells, mucosal‐associated …

As humans age, their memory T cell compartment expands due to the lifelong exposure to
antigens. This expansion is characterized by terminally differentiated CD8+ T cells (Temra) …

Immunosenescence is a physiological process that is associated with changes in the
immune system, particularly among CD8 T-cells. Recent studies have hypothesized that …

Killer immunoglobulin-like receptors (KIRs) are polymorphic receptors for human leukocyte
antigens (HLAs) that provide positive or negative signals controlling lymphocyte activation …

Here, we present a protocol for setting three spectral flow cytometry panels for the
characterization of human unconventional CD8+ NKG2A/C+ T cells as well as other T and …

Did you experience working in a country with more than half year raining and half year off-
work? Did you work without sun whole day? Did you experience that doing a big experiment …

Les lymphocytes T CD8 innés, une nouvelle population T non conventionnelle (re)programmée
en transplantation rénale Page 1 THÈSE Pour l'obtention du grade de DOCTEUR DE L'UNIVERSITÉ …